研究发表/论文

本公司在各个领域与大学、公共机关、企业一起积极推进共同研究,并在论文等中发表了其成果。关于近年来的发表,我来介绍一下其中的一部分。

基因工程相关/其他

  • 集成和使用模块化防盗板B Virus Core Protein for a Comprehensive Interactome Analysis
    Y.Nakai,K.Miyakawa,Y.Yamaoka,Y.Hatayama,M.Nishi,H.Suzuki,H.Kimura,H.Takahashi,Y.Kimura,A.Ryo
    icroorganisms,102381(2022)。
  • 不动不动目标HTLV-1环境gp46 Glycoprotein and Its Application to Near-Infrared Photoimmuno-Antimicrobial Strategy
    Y.Hatayama,Y.Yamaoka,T.Morita,S.S.Jeremiah,K.Miyakawa,M.Nishi,Y.Kimura,M.Mitsunaga,T.Iwase,H.Kimura,N.Yamamoto,A.Takaori-Kondo,H.Hasegawa,A.Ryo
    Viruses,142153(2022)。
  • 部分读出监视主机Spectrometry Assay for the Development of Norovirus Major Capsid Protein
    Y.Kimura,J.Shin,Y.Nakai,M.Takahashi,Y.Ino,T.Akiyama,K.Goto,N.Nagata,Y.Yamaoka,K.Miyakawa,H.Kimura,A.Ryo
    Viruses,14(7),1416(2022)。
  • Spike Protein Synthesized by Wheat Germ Cell-Freee Production System
    Y.Yamaoka,S.S.Jeremiah,R.Funabashi,K.Miyakawa,T.Morita,Y.Mihana,H.Kato,A.Ryo
    Viruses,14(7),1461(2022)。
  • Vaccine-induced humoral response against SARS-CoV-2 dramatically declined but cellular immunity possibly remained at6 months post BNT162b2 vaccination
    H.Kato,K.Miyakawa,N.Ohtake,Y.Yamaoka,S.Yajima,E.Yamazaki,T.Shimada,A.Goto,H.Nakajima,A.Ryo
    Vaccine,402652-2655(2022)。
  • Molecular and Epidemiological Characterization of Emerging Immune-Escape Variants of SARS-CoV-2
    K.Miyakawa,S.S.S.Jeremiah,Y.Yamaoka,T.Koyama,R.Tokumasu,M.Kudo,H.Kato,A.Ryo
    frontiers in Medicine,10(2022)。
  • 针对新型冠状病毒感染症的抗原检查法
    山冈悠太郎、宫川敬、森田武志、梁明秀
    感染控制和预防卫生,5(2),8-14(2021)。
  • Antibody titers against the Alpha,Beta,Gamma,and Delta variants of SARS-Cov-2induced byBNT162b2vaccination measured using automated chemiluminescent enzyme immunoassay
    H.Kato,K.Miyakawa,N.Ohtake,H.Go,Y.Yamaoka,S.Yajima,T.Shimada,A.Goto,H.Nakajima,A.Ryo
    Journal of Infection and Chemotherapy,28273-278(2022)。
  • 2019 Convalescent Individuals Over12 Months After Infection
    K.Miyakawa,S.Kubo,S.S.S.Jeremiah,H.Go,Y.Yamaoka,N.Ohtake,H.Kato,S.Ikeda,T.Mihara,I.Matsuba,N.Sanno,M.Miyakawa,M.Shinkai,T.Miyazaki,T.Ogura,S.Ito,T.Kaneko,K.Yamoto,A.Goto,Ryo
    Open Forum Infectious Diseases,9(2),ofab626(2022)。
  • All Trans Retinoic Acid Exhibits Antiviral Effect against SARS-COV-2by Inhibiting3CLpro Activity
    T.Morita,K.Miyakawa,S.S.Jeremiah,Y.Yamaoka,M.Sada,T.Kuniyoshi,J.Yang,H.Kimura,A.Ryo
    Viruses,13(8),1669(2021)。
  • 新型冠状病毒抑制剂筛选法的研制及其应用
    森田武志、宫川敬、山冈悠太郎、国吉智子、梁明秀
    FRAGRANCE JOURNAL,6,32-38(2021)。
  • 新型冠状病毒感染症的病情和免疫
    久保创介、山冈悠太郎、宫川敬、梁明秀
    传染病和预防卫生,5(1),10-17(2021)。
  • Combining IL-6and SARS-COV-2RNAaemiabased risk stratification for fatal outcomes of COVID-19
    R.Saji,M.Nishii,K.Sakai,K.Miyakawa,Y.Yamaoka,T.Ban,T.Abe,Y.Ohyama,K.Nakajima,T.Hiromi,R.Matsumura,N.Suzuki,H.Taniguchi,T.Otsuka,Y.Oi,F.Ogawa,M.Uchiyama,K.Takahashi,M.Iwashita,mura.Furui.,T.Tamura,A.Ryo,I.Takeuchi
    PLoSONE16(8):e0256022(2021)。
  • Highly specific monoclonal antibodies and epitope identification against SARS-CoV-2 nucleocapsid protein for antigen detection tests
    Y.Yamaoka,K.Miyakawa,S.S.S.Jeremiah,R.Funabashi,K.Okudela,S.Kikuchi,J.Katada,A.Wada,T.Takei,M.Nishi,K.Shimizu,H.Ozawa,S.Usuku,C.Kawakami,N.Tanaka,T.Morita,H.Hayashi,H.Mitsukii,Suzuki,Azwa.Yoshimura,T.Miyazaki,E.Yamazaki,T.Suzuki,H.Kimura,H.Shimizu,N.Okabe,H.Hasegawa,A.Ryo
    Cell Reports Medicine(2021)。doi:10.1016/j.xcrm.2021.100311
  • Sustained Neutralizing Antibodies 6 Months Following Infection in 376 Japan ese COVID-19 Survivors
    A.Goto,H.Go,K.Miyakawa,Y.Yamaoka,N.Ohtake,S.Kubo,S.Jeremiah,T.Mihara,K.Senuki,T.Miyazaki,S.Ikeda,T.Ogura,H.Kato,I.Matsuba,N.Sanno,M.Miyakawa,H.Ozaki,M.Kikuoka,Y.Ohashi,A.Yamayo
    frontiers in Microbiology(2021)。doi:10.3389/fmicb.2021.661187
  • Severe acute respiratory syndrome coronavirus2 prevalence in saliva and gastric and intestinal fluid in patients undergoing gastrointestinal endoscopy in coronaviruse2019 endemic areas:Prospective cross-sectional study in Japan
    S.Miyake,K.Ashikari,S.Kato,T.Takatsu,H.Kuwashima,H.Kaneko,K.Nagai,I.Watari,T.Sato,Y.Yamaoka,T.Yamamoto,A.Ryo,S.Maeda,A.Nakajima,T.Higurashi
    Digestive Endoscopy(2021),doi:10.11111/den.13945
  • 第三代Monoclonal Antibodies and Antigen-Capture ELISA forHuman Parechovirus Type 3
    K.Goto,Y.Yamaoka,H.Khatun,K.Miyakawa,M.Nishi,N.Nagata,T.Yanaoka,H.Kimura,A.Ryo
    icroorganisms,81437(2020)。
  • Rapid multiplex microfiber-based immunoassay for anti-MERS-CoV antibody detection
    C.F.O.Hoy,K.Kushiro,Y.Yamaoka,A.Ryo,M.Takai
    Sensing and Bio-Sensing Research,26,Article100304(2019)。
  • 生产和characterization of monoclonal antibodies specific for major capsid VP1 protein of trichodyspasia spinulosa associated polyomavirus
    H.Khatun,Y.Yamaoka,Y.Matsushima,S.Matsunaga,H.Kimura,J.Ho,M.Shuda,A.Ryo
    icrobiology and Immunology,62(12),763-773(2018)。
  • 不可拆卸地安装到基座上identify hepatitis B virus entry inhibitors targeting the sodium taurocholate cotransporting polypeptide
    K.Miyakawa,S.Matsunaga,Y.Yamaoka,M.Dairaku,K.Fukano,H.Kimura,T.Chimuro,H.Nishitsuji,K.Watashi,K.Shimotohno,T.Wakita,A.Ryo
    Oncotarget,9(34),23681-23694(2018)。
  • DNA amplification for development of abench-top extracleanroom
    H.Takahashi,T.Satoh,H.Kanahara,Y.Kubota,T.Hirose,H.Yamazaki,K.Yamamoto,Y.Okamura,T.Suzuki,T.Kobori
    BioTechnique,61(1),42-46(2016)。
  • 预应力桥墩墩支护板,支护板,支护板,支护板,支护板
    T.Chimuro,H.Kuroyama,Y.Goso,K.Ishihara,M.Kurihara
    Carbohydrate Research,43276-82(2016)。
  • 用于诊断的模块化防波堤和诊断测试的模块化East Respiratory Syndrome Coronavirus Using Cell-Free Synthesized Nucleocapsid Antigen
    Y.Yamaoka,S.Matsuyama,S.Fukushi,S.Matsunaga,Y.Matsushima,H.Kuroyama,H.Kimura,M.Takeda,T.Chimuro,A.Ryo
    Frontiers in Microbiology,7509(2016)。
  • 面向微生物1细胞基因组分析的全基因组扩增法的改良
    高桥宏和、山崎裕之、小堀俊郎
    生物科学与工业,72(6),492-493(2014)。
  • Preparation of Phi29 DNA Polymerase Free of Amplifiable DNA Using Ethidium Monoazide,an Ultraviolet-Freee Light-Emitting Diode Lamp and Trehalose
    H.Takahashi,H.Yamazaki,S.Akanuma,H.Kanahara,T.Saito,T.Chimuro,T.Kobayashi,T.Ohtani,K.Yamamoto,S.Sugiyama,T.Kobori
    PLOS ONE,9(2),e82624/1-e82624/9(2014)。

细胞培养相关

  • 活动imaging-friendly slice culture method using collagen membranes
    A.Ogaki,T.Araki,M.Ishikawa,Y.Ikegaya,R.Koyama
    Neuropsychopharmacology Reports,40307-313(2020)。
  • 多层次Validation Study of the Vitrigel-Eye Irritancy Test Method as an Alternative to In Vivo Eye Irritation Testing
    H.Kojima,H.Yamaguchi,T.Sozu,N.Kleinstreuer,L.Chae-Hyung,W.Chen,M.Watanabe,T.Fukuda,K.Yamashita,T.Takezawa
    Alternatives to Laboratory Animals,47(3-4),140-157(2019)。
  • Collagen vitrigel promotes hepatocytic differentation of induced pluripotent stem cells into functional hepatocyte-like cells
    S.Nakai,I.Shibata,T.Shitamichi,H.Yamaguchi,N.Takagi,T.Inoue,T.Nakagawa,J.Kiyokawa,S.Wakabayashi,T.Miyoshi,E.Higashi,S.Ishida,N.Shiraki,S.Kume
    Biology Open,8,bio042192(2019)。
  • corneal epithelial and endothelial cells via collagen vitrigel membrane functioned asan acellular stroma and its application to the corneal permeability test of chemicals
    H.Yamaguchi,T.Takezawa
    Drug Metabolism and Disposition,46(11),1684-1691(2018)。
  • 动物实验替代方法中皮肤评价模型的制作与评价
    使用胶原三凝胶膜室的眼刺激性试验法

    竹泽俊明、山口宏之
    皮肤的安全性·有用性评价法、株式会社技术信息协会、2018、pp.73-77。
  • 前瞻性性能测试118 chemicals
    H.Yamaguchi,H.Kojima,T.Takezawa
    Journal of Applied Toxicology,36(8),1025-1037(2016)。
  • 流动dwell impact induces peritoneal fibrosis in the peritoneal cavity reconstructed in vitro
    Aoki,M.Noguchi,T.Takezawa,S.Ikeda,K.Uchihashi,H.Kuroyama,T.Cimuro,S.Toda
    Journal of Artificial Organs,19(1),87-96(2016)。
  • 适合三维培养的新细胞培养用器材ad-MED®
    高木信幸
    清洁技术,2014(3),71-74(2014)。

诊断试剂相关

  • 高精度传感器和rapid antigen detection assay for diagnosis of COVID-19 utilizing optical waveguide immunosensor
    R.Funabashi,K.Miyakawa,Y.Yamaoka,S.Yoshimura,S.Yamane,J.S.Stanleyraj,K.Shimizu,H.Ozawa,C.Kawakami,S.Usuku,N.Tanaka,E.Yamazaki,H.Kimura,H.Hasegawa,A.Ryo
    Journal of Molecular Cell Biology,mjab037(2021)。
  • 新型冠状病毒的抗原·抗体检查法
    山冈悠太郎、梁明秀
    神奈川县公共卫生学会志,第66号(2021)。
  • 新型冠状病毒感染症的检查诊断法
    山冈悠太郎、梁明秀
    感染控制和预防卫生,4(1),9-15(2020)。

微生物检查相关

  • 不需要厌氧培养C。Diff选择增菌培养基的性能评价
    大川内沙织、名取达矢、内田宣邦、新井惠理子、堀内一树
    日本临床微生物学会杂志,32(4),63-66(2022)。

电泳相关/其他

  • 蛋白质检测用荧光分子探针的创制和向高通量检测法的展开
    铃木祥夫、高木信幸
    生物物理化学,58(2),65-67(2014)。

有机合成·催化剂关联

  • ammonia removal in livestock farms based on copper hexacyanoferrate granules
    K.Minami,A.Takahashi,K.Sakurai,H.Mikasa,M.Takasaki,N.Doshu,K.Aoyama,T.Nakamura,R.IaIwai,T.Kawamoto
    Biosystems Engineering,216,98-107(2022)。
  • Asymmetric Transfer Hydrogenative Amination of Benzylic Ketones Catalyzed by Cp*Ir(III)Complexes Bearing a ChiralN-(2-Picolyl)sulfonamidato Ligand
    T.Kawada,K.Yabushita,T.Yasuda,T.Ohta,T.Yajima,K.Tanaka,N.Utsumi,M.Watanabe,K.Murata,Y.Kayaki,S.Kuwata,and T.Katayama
    The Journal of Organic Chemistry,87(13),8458-8468(2022)doi;10.1021/acs.joc.2c00580
  • 双支座,双支座,双支座,双支座,双支座,双支座,双支座
    K.Kato,K.Takaba,S.M-Yonekura,N.Mitoma,Y.Nakanishi,T.Nishihara,T.Hatakeyama,T.Kawada,Y.Hijikata,J.Pirillo,L.T.Scott,K.Yonekura,Y.Segawa,K.Itami
    American Chemical Society,doi;10.1021/jacs.1c00863
  • (III)Complexes Bearing a Picolinamidato Ligand
    K.Tanaka,T.Miki,K.Murata,A.Yamaguchi,Y.Kayaki,S.Kuwata,T.Ikariya,M.Watanabe
    The Journal of Organic Chemistry,8410962-10977(2019)。
  • Asymmetric Hydrogenation of Polysubstituted Aromatic Ketones Catalyzed by the DIPSkewphos/PICA Derivative–Ruthenium(II)Complexes
    N.Utsumi,N.Arai,K.Kawaguchi,T.Katayama,T.Yasuda,K.Murata,T.Ohkuma
    ChemCatChem,10(18),3955-39592018。
  • 计算机许可证修改using Interplay between Theory and Experiments:Highly Active Chiral Rhodium Catalyst Controlled by Electronic Effects and CH-πInteractions
    T.Korenaga,R.Sasaki,T.Takemoto,T.Yasuda,M.Watanabe
    高级Synthesis&Catalysis,360322-333,(2018)。
  • Palladium-Catalyzed Decarbonylative Cross-Coupling of Azinecarboxylates with Arylboronic Acids
    K.Muto,T.Hatakeyama,K.Itami,J.Yamaguchi
    Organic Letters,18(19),5106-5109(2016)。
  • C-H arylation and alkenylation of imidazoles by nickel catalysis:solvent-accelerated imidazole C-H activation
    K.Muto,T.Hatakeyama,J.Yamaguchi,K.Itami
    Chemical Science,66792-6798(2015)。
  • 地下排水管道施工法
    N.Arai,N.Onodera,A.Dekita,J.Hori,T.Ohkuma
    Tetrahedron Letters,56(25),3913-3915(2015)。

有机材料相关

  • 离子性高分子胶凝剂的开发
    高桥崎干大
    月度精细化学,45(10),47-55(2016)。
  • Novel Hole-Transporting Materials with High Triplet Energy for Highly Efficient and Stable Organic Light-Emitting Diodes
    H.Fukagawa,T.Shimizu,H.Kawano,S.Yui,T.Shinnai,A.Iwai,K.Tsuchiya,T.Yamamoto
    The Jounal of Physical Chemistry C,120(33),18748-18755(2016)。

电子工业用药品相关

无机材料关联

  • 将用聚乙烯醇造粒铁氰化铜用于Cs吸附材料的离子色谱法对137Cs浓缩飞灰的去污
    市川恒树、山田一夫、岩井良太、金泽幸广
    环境放射能除污学会志,8(2),55-66(2020)。
  • 分析管接头支座座座座的壁面支座
    G.Kido,M.Takasaki,K.Minami,H.Tanaka,H.Ogawa,T.Kawamoto,K.Yoshino
    Journal of nuclear science and technology,54(11),1157-1162(2017)。
  • 不平衡过热器支架
    K.M.Lee,M.Asai,T.Uchida,T.Kawamoto,K.Minami,A.Takahashi,D.Parajuli,G.Kido,M.Takasaki,K.Yoshino,H.Tanaka
    Chemistry Letters,45(6),670-672(2016)。
  • granulated copper hexacyanoferrate with multi-scale porous networks
    K.M.Lee,T.Kawamoto,K.Minami,A.Takahashi,D.Parajuli,G.Kido,K.Yoshino,H.Tanaka
    RSC Advances,616234-16238(2016)。
  • 计算机辅助系统的仪表板,仪表板,仪表板,仪表板,仪表板,仪表板,仪表板,仪表板
    D.Parajuli,A.Takahashi,H.Noguchi,A.Kitajima,H.Tanaka,M.Takasaki,K.Yoshino,T.Kawamoto
    Chemical Engineering Journal,2831322-1328(2016)。
  • 应用程序在轨道上的active Cs decontamination in Fukushima region
    D.Parajuli,A.Kitajima,A.Takahashi,H.Tanaka,H.Ogawa,Y.Hakuta,K.Yoshino,T.Funahashi,M.Yamaguchi,M.Osada,T.Kawamoto
    Journal of Environmental Radioactivity,151233-237(2016)。
  • Prusian blue(PB)granules for cesium(Cs)removal from drinking water
    G.Ru.Chen,Y.R.Chang,X.Liu,T.Kawamoto,H.Tanaka,A.Kitajima,D.Parajuli,M.Takasaki,K.Yoshino,M.L.Chen,Y.K.Lo,Z.Lei,D.J.Lee
    Separation and Purification Technology,14316-151(2015)。