Gram(+)cocci pose a global threat to human health due to the emergence of resistance to antibiotics。Linezolid has a broad spectrum of activity against a variety of pathogenic Gram(+)microorganisms,such as MRSA,VRS,and VRE。强制强制强制执行(LIN-R)和强制执行(resistance)linked to the horizontal spread of resistance linked to thecfrgene,have been increasingly reported after approval of its clinical use。
Although the prevalence of linezolid resistance remains low,the emergence of LIN-R strains is still of great concern。Today,linezolid sensitivity in Gram(+)clinical specimens is primarily monitored by surveillance programs in Europe and in the United States。Clinical isolates for surveillance of LIN-R strains include swabs from the nose(for screening ofStaphylococcus),perianal and rectal areas(for screening ofEnterococcus)。
CHROMagar™,™LIN-R is a chromogenic screening medium for the detection,isolation and differentation of strains ofStaphylococcusand,andEnterococcusresistant to linezolid。