- Foreign name
- specific
- Common causes
- Cancer
- common symptom
- Different types of symptoms
- Western medicine name
- Specificity
- Department
- Internal Medicine - Department of Oncology
- anniversaries of important events
- February 4, World Cancer Day
- Whether included in medical insurance
- yes
- Clinical
- Specific anti-tumor immunotherapy
1. Pairing, the inevitable corresponding selection relationship between grouped objects. For example, one key has one lock, and the existence of the key has a specific corresponding lock.
For example, enzyme substrate antigen -Antibodies Ligands -Reciprocal discrimination and selective binding reactions between receptors are corresponding from the perspective of stereo structure reactant Conformational correspondence between. The specificity of an enzyme means that an enzyme can distinguish between two or more different substrates, and combine with one of the most suitable substrates in its conformation to catalyze the chemical reaction of the substrate, showing that the enzyme has strict selectivity to its substrate. This phenomenon can be explained by the induced wedge theory, that is, when the enzyme is close to the substrate, it can induce the enzyme protein to change its structure. On this basis, the enzyme and substrate were complementary wedged to react. X-ray diffraction analysis showed that there were significant conformational changes when the enzyme combined with the substrate. two Observation object The value of an indicator property different from its source group. Plant variety specificity: it means that the new plant variety for which the variety right is applied should be significantly different from the known plant variety before the application is submitted.
DNA Match specificity: it refers to the obvious difference between the DNA to be tested and the contrast material. Put forward the meaning of point 2 based on（ Medical Statistics ）Of susceptibility And specificity: stay Medical statistics Any one of them Diagnostic indicators Both of them have two basic characteristics, namely sensitivity and specificity. The so-called sensitivity means that they do not miss diagnosis when diagnosing diseases（ false negative ）What is the chance (small) of? The so-called specificity means that the indicator will not be misdiagnosed when diagnosing a disease（ false positive ）What are the opportunities. （1） sensitivity , that is, the number of positive test samples in the total number of patients percentage ； For example, cold patient, routine blood test The rate of high white blood cell count in middle blood; (2) Specificity, that is, the percentage of negative test samples among healthy people in the total number of healthy people;
（3） positive predictive value , that is, the percentage of patient samples in the total number of positive test samples; （4） negative predictive value That is, the percentage of normal samples in the total number of negative test samples. The healthy people mentioned in specificity are relative, referring to people who have not observed diseases, such as those in research tumour Indicator for gastric cancer When the specificity of, gastric ulcer Patients are also healthy people. Your detection standard may not be able to get all negative results in the gastric ulcer group. If you cannot get all negative results, this group of data shows the probability of misdiagnosis of normal people. 
