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Beijing Institute of Biological Products

Microbiology, immunology research and anti epidemic products production unit
synonym Institute of Biology (Community of Chengdu Institute of Biological Products) generally refers to Beijing Institute of Biological Products
Beijing Institute of Biological Products microbiology Units engaged in immunology research and production of epidemic prevention products, with 1473 employees Scientific and technical personnel 612, accounting for 42% of the total number of employees. Among them, there are 88 senior technicians and 170 intermediate technicians.
On August 5, 2020, the production workshop of Beijing Institute of Biological Products' Xinguan Inactivated Vaccine passed the Bio-Safety Joint inspection , become the first Inactivated neocoronal vaccine Workshop. [1]
On May 7, 2021, world health organization Announced that Inactivated neocoronal vaccine Formally adopted World Health Organization Emergency use certification. [2-3]
July 16, 2021 Joint prevention and control mechanism of the State Council Relevant departments organize demonstration, Sinopharm Group Chinese Biology Beijing Institute of Biological Products Inactivated coronavirus vaccine It is approved for emergency use among people aged 3-17. China's inactivated COVID-19 vaccine was officially approved for emergency use in this age group. [4-5]
Chinese name
Beijing Institute of Biological Products
Date of establishment
1919
Predecessor
Central Epidemic Prevention Office of Beiyang Government
Address
The former site of the Shenyue Temple in the southwest corner of the Temple of Heaven
area covered
560000 m ²
built-up area
110000 m ²

Project Introduction

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LOGO
The institute is not only a unit that develops important research projects and successfully develops and popularizes important epidemic prevention products, but also an early research institute in China antibiotics Units of.
It is the first specialized agency for national health and epidemic prevention and serum vaccine research and production in China's history. In the following three decades, Beijing has moved several times and gone through hardships to develop and produce the earliest Vaccinia cholera Typhoid fever hydrophobia vaccine and Diphtheria antitoxin 15 kinds of products; The first strain isolated in China penicillin The strain has achieved the breakthrough of zero biological products in China, continued and developed the cause of biological products in China, trained and trained professionals, and laid the foundation for the development of biological products in China.
New China was founded Later, Beijing Institute and the Republic developed together and became more prosperous. Scientific and technological achievements triumphant news, Asset size The variety benefit is rising with continuous expansion. Tang Feifan Et al Chlamydia trachomatis , access to international trachoma Issued by the organization Gold medal , is an important discovery in the world pathogen The first Chinese to win this honor, and the only Chinese to win this honor so far; Zhao Bao Successful organizational research and development Chicken embryo cell culture Instead of animal inoculation preparation Vaccinia vaccine , for control smallpox Even the eradication of smallpox has made outstanding contributions; freezing Drying technology Viruses Sexual vaccine cell culture technique Apheresis Plasma Technology, biochemical technology for biological product verification, and blood source hepatitis B vaccine Rubella vaccine , inactivated JE vaccine and other vaccines were first produced in Beijing. At the same time, Beijing Institute and International Health Organization The contact and cooperation with relevant research institutes in various countries are increasingly strengthened. The English abbreviation of Beijing Institute is "NVSI" (National Vaccine and Service Institute), which enjoys a high reputation in the world. In the past 50 years, Beijing Institute, together with its brother Institute of Biological Products Hygiene and epidemic prevention The colleagues of the system work together to prevent diseases Disinfestation We have made great contributions to protecting people's lives and health.
Since 1998, Beijing Institute has entered a new Development stage , the first listed company in China's biological products industry—— Beijing Tiantan Biological Products Co., Ltd (Tiantan creature) was born. Beijing Stock Exchange reorganized high-quality assets and established Tiantan Biology by raising funds. Shanghai Securities and Exchange Commission on June 16, 1998 Listing of shares Beijing Stock Exchange held 75% of the shares during the issuance, and after several additional issuance, the holding shares of Beijing Stock Exchange were changed to 56.27%. Tiantan Biology has insisted on inheritance, innovation and development for more than ten years since it was listed Operation mode The company has made steady development and achieved remarkable achievements. Beijing Institute has made great efforts to adapt to the new situation and gradually shifted the focus of its work to the track of focusing on scientific research. During this period, Beijing moved forward with firm exploration and worked hard in the pain of change. Scientific research work has never been mentioned to a higher position and height. Increase scientific research investment, improve scientific research conditions Management mechanism Gradually identical market economy In line with the practice, the training and introduction of scientific research talents and the progress of research projects have become the top priorities of the whole institute. In the past ten years, VERO cell inactivated JE vaccine Leprosy Duplex MMR vaccine And injected new vitality into the development of Tiantan biology.
By the end of 2008, Beijing Institute had won more than 100 domestic and foreign awards, including one international gold award Scientific and technological progress Two first prizes, other national level prize for science and technology progresses 16, 36 ministerial awards for scientific and technological progress, and a group of influential scientists and scientific and technical worker
Since 1983, Beijing Institute has started to recruit Basic Medicine Master , including immunology In the past 20 years, nearly 200 graduate students have been trained in two professional research directions, namely, pathogen biology and pathogen biology. Going to work has become the technical backbone of the industry.
Chinese Medical Association The national first-class magazine "Chinese Journal of Microbiology and Immunology" sponsored by Beijing Institute and supported by Beijing Institute has won the National Excellent Journal Award for many times.
In order to better meet the rapid development and challenges of international biotechnology and promote China Biological industry Vigorously developed in the National Development and Reform Commission and Beijing With the support of Beijing Municipal People's Government and the direct participation of the group company, Beijing Institute seized the opportunity to jointly set up the“ National Engineering Research Center for New Vaccines ”(Vaccine Center). The base construction of the Vaccine Center has been capped in Yizhuang Development Zone by the end of 2009. The first phase investment is more than 200 million yuan. Five pilot production lines, integrated laboratories and related facilities will be built in line with international standards supporting facilities Comprehensive scientific research building, Total building area More than 20000 square meters, mainly engaged in research and development Independent intellectual property rights Of New vaccines Focus on establishment Gene recombination Technology Mammalian cell Large scale cultivation technology Combined vaccine Conjugate vaccine Technology DNA and Polypeptide synthesis Technology Humanization Monoclonal antibody The key technology platform for research and development of biological products such as technology is expected to be delivered by the end of 2010.
Beijing Institute and Vaccine Center have nearly 30 research projects in progress, and have a team of High quality talents ranks. Academician Zhao Jia and Shanghai Fudan University Wen Yumei Academicians cooperate for treatment Chronic hepatitis B Country of A class of new drugs "Yike" has successfully completed Phase I and Phase II clinical research , Phase III clinical study is in progress; EV71 vaccine research and other national priorities supported by the Ministry of Science and Technology and led by the Vaccine Center R&D projects We have also made phased progress. Beijing Institute and Vaccine Center have won 25 national support projects independently or jointly with other units, and have received nearly 100 million yuan of financial support. Beijing Institute and Vaccine Center are gradually forming multidisciplinary, multi project, independent R&D and Cooperative R&D Combined with medium and long-term projects Research and development System. A more scientific, modern and industrialized biotechnology platform is being formed with advanced technique And the scientific research force with vigorous fighting spirit is ready to be launched.

research findings

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late Tang Feifan The professor first successfully isolated chlamydia trachomatis in the world and won the gold medal of "International Trachoma Organization"; The first blood source successfully developed in China hepatitis B vaccine Won the first prize of National Science and Technology Progress Award; In addition, more than 60 scientific research achievements have won various awards from the state, the Ministry of Health and other departments. With the development of modern biotechnology, the Institute will give full play to the advantages of traditional biotechnology genetic engineering cell engineering molecular biology And other fields to achieve key development and build China Modern biotechnology An important development base of products.
Ministry of Health 291-1.jpg (10723 bytes) world health organization Keep in close contact. Some famous international scholars and officials of the World Health Organization have visited the place for many times, which has reached 600 person times since 1978; The Institute scientific and technical personnel 200 experts were successively sent abroad for further study, investigation or to attend international conferences. Chen Zhengren Zhang Yihao , Su Wannian and other experts have successively served as global Expanded immunization programme panel of consultants Members.
On March 3, 2022, Beijing Institute of Biological Products Wuhan Institute of Bio Products Determined with Hong Kong research institute Clinical protocol And relevant details, on March 26 and 30, respectively, Chinese drugs and food were obtained test The verification qualification report of the research institute was submitted to the Hong Kong Department of Health The clinical application materials were submitted, and the ethical approval was obtained on April 12, and the clinical research approval was obtained on April 13, making it the first Omicron strain approved for clinical use in the world Live vaccine. [7]
April 2022, by Sinopharm Group Chinese Biology Two models developed by Beijing Institute of Biological Products and Wuhan Institute of Biological Products Novel inactivated coronavirus vaccine (Omikjon mutant, hereinafter referred to as "O strain") University of Hong Kong and Health Administration Hong Kong Island Research on Western Hospital Networking Ethics Committee And Hong Kong Pharmacy and Poisons Administration The approval document for clinical trial of was officially approved to be carried out in Hong Kong New coronal vaccine Sequential immunoclinic of Research. [6]
According to "Chinese Biology" WeChat official account News: On May 9, 2022, the sequential clinical trial of the Aomikerong inactivated coronavirus vaccine of Sinopharm Biotech Beijing Institute of Biological Products Hunan Provincial launch. [8]
In May 2023, Sinopharm China Biotech Beijing Institute of Biological Products ACYW135 meningococcal polysaccharide vaccine was officially approved City. [9]

cooperation

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country planned immunization Technical Consultation Committee Secretariat, China Denmark The Sino Danish Medical Biology Graduate Training Center, the editorial department of Chinese Journal of Microbiology and Immunology Chinese Preventive Medicine Association The branches of biological products are all located in the institute, and they are responsible for the training of high-energy technicians, the technical guidance of planned immunization academic exchange Consulting Technology transfer And other aspects to serve the country and face the world. Ministry of Health 291-2. jpg (12523 bytes )

Other information

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The institute produces various epidemic prevention products Blood products And diagnostic supplies Infectious Diseases And made important contributions to improving people's health and prolonging people's life span.
The office is located in three rooms in Chaoyang, with a beautiful environment and a hundred miles to the south Chang'an Street Jianguo Road, north Chaoyang Road It has direct access to the city center, convenient transportation and good communication conditions.