Department of Dermatology, Peking University People's Hospital
Ding Xiaolan
Attending physician (written)
Department of Dermatology, Peking University People's Hospital
Liu Zhengyi
Resident physician (writing)
Department of Dermatology, Peking University People's Hospital
Seborrheic keratosis (SK) is also called senile wartSenile plaquesBasal cell papillomaBenign skin tumor, which tends to happen to middle-aged and elderly people, becauseKeratinocytesBenign hyperplasia of epidermis caused by hyperplasia.SK is good at facial headbackAnd the back of the hand.
It is reported that SK has obvious familial tendency, and it is speculated that this disease may be aIncomplete penetranceOfAutosomal dominant disease。Although the disease is common clinically, there are few statistical reports on its incidence, gender or ethnic orientation and regional distribution.The disease is more common in white people, with the same incidence of men and women.This disease is rare in people under 40 years old.
pathogeny
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Sunlight exposure may be related to the occurrence of SK.
clinical manifestation
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The disease mostly occurs after the age of 40, mainly in scalp, face, trunk, upper limbs, back of hand and other parts, but does not involve palms and soles.It starts with light brown spots orFlat papule, the surface is smooth or slightlyPapillomaIt is shaped like a papilloma, and increases with age, with a diameter of 1mm~1cm, or several centimeters. The boundary is clear, the surface is papilloma like, and there is greasy scab on the surface, which is easy to scrape off.The pigmentation of some lesions can be very significant, dark brown or black. The color of old lesions varies greatly, and can be normal skin color, light brown, dark brown or black.This disease cansingle shotHowever, it usually occurs frequently without conscious symptoms and occasionally itches.Skin lesions develop slowly and rarely deteriorate.There are several special types in clinic:
1. Irritating seborrheic keratosis
It occurs at the overflow or friction part of the cortex. The skin lesions may be inflamed due to stimulation. The base turns red and the surface shows irregular hyperplasia.
2. Eruptive seborrheic keratosis
It occurs suddenly and increases rapidly in the short term.Attention should be paid to whether there are concurrent visceratumour。
This disease generally does not need treatment.For cases with unclear diagnosisSkin lesionMake a histopathological examination.When treatment is needed for cosmetic reasonsCO2 laser, liquid nitrogen freezingErbium laser、CurettageOr surgical resection.
