Cancer cell diffusion process:cancerCells are in the process of metastasisChina CouncilWhen encountering many difficulties, first we have to undergo dozens of mutations, then we have to overcome the intercellular adhesion and break away, and change the shape to pass through the denseconnective tissue。After successful escape, cancer cells will pass throughcapillaryInto the blood, where it may also bewhite blood cellAttack.Next, cancer cells will enter a new organ through microvessels (now called "micrometastasis").
Scientists point out that cancer cells are in the process of metastasisChina CouncilWhen encountering many difficulties, first we have to undergo dozens of mutations, then we have to overcome the intercellular adhesion and break away, and change the shape to pass through the denseconnective tissue。After successful escape, cancer cells will pass throughcapillaryInto the blood, where it may also be attacked by white blood cells.Next, cancer cells will enter a new organ through microvessels (now called "micrometastasis").Here, cancer cells face an unfriendly environment (called“Microenvironment”）Some cells die immediately, some die after several divisions, and some remainSleep state，Survival rateOnly a few hundred million.Surviving cancer cells can regenerate and colonize, becoming "metastasis visible to the naked eye" that can be found in laboratory tests.With the development of metastasis, it squeezes out normal cells and destroys the function of organs, which is fatal in the end.clinical research Indicates that it is in useMalt seleniumstaySuppressor cellIn the process of transferHindranceAnd can stimulate sleeping cancer cells to help kill and reduceRecurrence rate。The research in this field has made a temporary breakthrough.
main cause
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Cancer is "rampant", often very restless, and quickly spread to other organs. Its nature is related to the growth mode of cancer and the characteristics of cancer cells.The reasons can be summarized as follows:
First, cancer cells proliferate rapidly. Due to the sharp increase in the number, the original space cannot accommodate so many cells, and the cells at the edge of the tumor are "squeezed" into the surrounding tissue.
Second, due to the special chemical composition and structure of the cancer cell surface, the adhesion between cancer cells is low, the connection is loose, and it is easy to separate from the cancer block, creating conditions for diffusion.
Third, cancer cells secrete special substances to dissolve and destroy surrounding tissues, opening the way for diffusion and metastasis.
In addition to the above reasons, there may be some factors that have not yet been recognized and understood by people, and these factors are complementary to each other.
Cancer cells and environment
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Generally speaking, cancer cells with poor differentiation have early metastasis, wide metastasis range and high malignancy;Well differentiated ones are less malignant.Why do different patients with the same type of cancer have different referral situations?This is related to the time of illness and the patient's physical condition.When cancer is in its early stage, there is less chance of metastasis and diffusion. If radical treatment can be carried out before metastasis and diffusion, the possibility of metastasis will be ruled out.When the treatment is carried out in the late stage, it will form a passive situation of smoke everywhere, which is impossible to prevent.In addition, good physical conditionResistanceStrong people may transfer later, and the scope of transfer is also limited.When the physical condition becomes worse and the resistance declines, the disease will deteriorate rapidly, and the cancer cells will spread unstoppably like a dam breach.
immunityIt is a natural barrier against diseases. If the immune function is unbalancedImmune surveillanceLoss of function, unable to clear mutant cells, also causestumourOne of the reasons.
Influence of pressure
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The pressure willcancerA lymph "highway" that helps cancer cells move freely is formed in the patient's body.
Pressure can makeMalignant tumorambientlymph glandThe liquid becomes thicker and morelymphatic systemIt seems that a "highway" has appeared in the body to spread cancer cells.
[1]The lymphatic system plays a role in transportingwhite blood cellAnd antibodies, which help the body fight against disease, but also deliver cancer cells. Pressure will stimulate lymphatic activity, making cancer cells move more freely.
