Organic compound
Collection
zero Useful+1
zero
synonym Nicotinamide mononucleotide (Chemicals) generally refers to NMN
NMN, Full name: β - nicotinamide nucleotide , Alias: Nicotinamide mononucleotide , pH value is 3.0-4.0, which is a natural biological activity Nucleotides, present in various organisms, [2] Same Cosmetic raw materials , white to yellowish, yes Crystallinity Powder, no obvious odor, dry and dark storage at room temperature, service life of 24 months, The chemical formula is C eleven H fifteen N two O eight P, yes Coenzyme I —— NAD + The key intermediate of the synthesis. [1-2] [4]
NMN is an inherent substance in the human body, which is also rich in some Fruits And vegetables. because nicotinamide It belongs to vitamin b3, so NMN belongs to the category of vitamin b derivatives. It is widely involved in many biochemical reactions in the human body immune Metabolism is closely related. [3]
Chinese name
NMN
Foreign name
β-Nicotinamide MononucleotideNMN
Alias
β - nicotinamide mononucleotide
chemical formula
C eleven H fifteen N two O eight P
molecular weight
three hundred and thirty-four point two one nine
CAS login number
1094-61-7
EINECS login number
214-136-5

molecular structure

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NMN, Full name: β - nicotinamide mononucleotide, chemical formula C eleven H fifteen N two O eight P, It is a naturally occurring bioactive nucleotide. Structurally, the molecule consists of nicotinamide group Ribose and phosphoric acid Base composition.
NAD+ Biosynthesis from NMN

Disputes

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There is still controversy about whether the anti-aging and life prolonging effects of nmn have human clinical significance. In December 2021, State Administration of Market Supervision In the Reply to the No. 1067 Recommendation of the Fourth Session of the 13th National People's Congress (hereinafter referred to as the Reply), it was stated that at present, the positioning and safety of nmn as a food raw material are still unclear, lacking Food Safety national standard , it is recommended to New food raw materials Carry out safety assessment or clarify national food safety standards. Nmn and Related products The health food has not been registered in China, and the condition of nmn as the raw material of health food is not yet mature, so further monitoring and research are needed.
The Reply also said that for nmn, China is currently in the research stage, China National Institute of Standardization and China Academy of Inspection and Quarantine Sciences Have the ability to carry out nmn Related research Capabilities, including the use history, security, functionality and function claims of nmn at home and abroad.
The supervision of nmn products is also increasingly strengthened. In January 2021, the State Administration of Market Supervision issued the Letter on Investigating the Illegal Operation of "Ageless Drugs", which clarifies that nmn cannot be produced and operated as food in China, and requires comprehensive investigation. [3]
In May 2023, the official website of the Health Commission issued a new batch of decisions on the denial of administrative license for new food additives, including 21 new varieties, such as NMN (β - nicotinamide mononucleotide), which is known as the "ageless drug". [5]

Progress

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January 24, 2022, NMN Cosmetic raw materials It has passed the record and is currently in the monitoring period. [1]