synonymNicotinamide mononucleotide(Chemicals) generally refers to NMN
NMN,Full name: β - nicotinamidenucleotide, Alias:Nicotinamide mononucleotide, pH value is 3.0-4.0, which is a naturalbiological activityNucleotides, present in various organisms,[2]SameCosmetic raw materials, white to yellowish, yesCrystallinityPowder, no obvious odor, dry and dark storage at room temperature, service life of 24 months,The chemical formula is CelevenHfifteenNtwoOeightP,yesCoenzyme I——NAD+The key intermediate of the synthesis.[1-2][4]
NMN is an inherent substance in the human body, which is also rich in someFruitsAnd vegetables.becausenicotinamideIt belongs to vitamin b3, so NMN belongs to the category of vitamin b derivatives. It is widely involved in many biochemical reactions in the human bodyimmuneMetabolism is closely related.[3]
NMN,Full name: β - nicotinamide mononucleotide, chemical formula CelevenHfifteenNtwoOeightP,It is a naturally occurring bioactive nucleotide.Structurally, the molecule consists of nicotinamide groupRiboseandphosphoric acidBase composition.
NAD+ Biosynthesis from NMN
Disputes
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There is still controversy about whether the anti-aging and life prolonging effects of nmn have human clinical significance.In December 2021,State Administration of Market SupervisionIn the Reply to the No. 1067 Recommendation of the Fourth Session of the 13th National People's Congress (hereinafter referred to as the Reply), it was stated that at present, the positioning and safety of nmn as a food raw material are still unclear, lackingFood Safetynational standard, it is recommended toNew food raw materialsCarry out safety assessment or clarify national food safety standards.Nmn andRelated productsThe health food has not been registered in China, and the condition of nmn as the raw material of health food is not yet mature, so further monitoring and research are needed.
The supervision of nmn products is also increasingly strengthened.In January 2021, the State Administration of Market Supervision issued the Letter on Investigating the Illegal Operation of "Ageless Drugs", which clarifies that nmn cannot be produced and operated as food in China, and requires comprehensive investigation.[3]
In May 2023, the official website of the Health Commission issued a new batch of decisions on the denial of administrative license for new food additives, including 21 new varieties, such as NMN (β - nicotinamide mononucleotide), which is known as the "ageless drug".[5]
Progress
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January 24, 2022, NMNCosmetic raw materialsIt has passed the record and is currently in the monitoring period.[1]