Sterol

chemical substances
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Sterol (English: sterol) Also called sterol, it is steroid One type of hydroxyl Steroids. They all use Cyclopentane phenanthrene It is the basic structure and contains hydroxyl, so it is called sterol compound.
use Alkaline solution To extract lipids from animal and plant tissues, there are often many different substances that cannot be saponified by alkali. There are many kinds of sterols, which are widely distributed in the biological world. as cholesterol Is high Animal cell Important components of. It is related to Long chain fatty acids The cholesterol ester formed is Plasma Lipoprotein And important components of cell membrane. plant cell The membrane contains other sterols such as Stigmasterol And sitosterol. Fungi and yeasts contain mycosterols.
Chinese name
Sterol
Foreign name
sterol
Alias
sterol
chemical formula
Consisting of three hexane rings and one cyclopentane
Category
steroid

Sterol information

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Class I consists of three hexane rings and one Cyclopentane Fused Cyclopentane phenanthrene Derivatives. It is widely found in the cells and tissues of animals and plants except for bacteria.
Sterol has many different biological functions, such as composition and composition of cell membrane Adrenocortical hormone and sex hormone Etc. not a few Plant sterol It also has strong pharmacological or toxicological effects, such as digitalis and waabain myocardium The contraction of is a treatment heart failure Good medicine. β - in plants Sitosterol , contained in yeast Ergosterol Cholesterol is the most abundant sterols in animals, which can be converted into sterol hormones in the body progesterone Estradiol testosterone cortisol and aldosterone Etc. Many contraceptives are derivatives of progesterone; Some testosterone analogues are Protein Biosynthesis Accelerator. 7-dehydrocholesterol can be converted into Vitamin D3 ( Cholecalciferol ), the latter can be converted into regulation in the body Calcium and phosphorus metabolism Hormone of 1,25-dihydroxycholecalciferol
cause Insect molting Of Ecdysin And anti staphylococcus It is also a sterol compound. Columbus The frog toxin secreted by Phyllobates aurotaenia can be blocked with only a small amount Nerve impulse Conduction between nerves and muscles. The end product of cholesterol metabolism in the body is bile acid And other sterols Biotransformation Increase its polarity and expel it from the body [1]

sterol

sterol
Sterol is an important natural active substance widely existing in organisms, which can be divided into animal sterols, plant sterols and fungus sterols according to the source of raw materials. Animal sterols are mainly cholesterol, while plant sterols are mainly sitosterol, stigmasterol, rapeseed oil sterol, etc Ergosterol It belongs to fungus sterol.

Phytosterol

Phytosterol It is widely found in roots, stems, leaves fruit And seed, yes plant cell The components of the membrane contain sterols in all oils from plant seeds. Phytosterols are insoluble in water, alkali and acid, but soluble in Ether , benzene, chloroform ethyl acetate Petroleum ether etc. Organic solvent in [2]

physiological function

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Prevention of cardiovascular diseases
Excessive intake of animal food or human regulatory function disorder will lead to high serum cholesterol concentration, which is easy to cause hypertension and coronary heart disease. Phytosterol can promote cholesterol dissimilation, inhibit cholesterol biosynthesis in the liver, and inhibit cholesterol absorption in the intestinal tract, thus preventing Cardiovascular disease Role of. Cholesterol is also an important component of cell membrane and participates in the transportation of lipids in the blood in the human body. [3]
Tumor inhibition
Phytosterols can block Carcinogen The function of inducing cancer cell formation, β - sitosterol Phytosterols and other phytosterols can inhibit the occurrence of colorectal cancer, skin cancer and cervical cancer to a certain extent.
stimulate metabolism
It is related to the reabsorption of renal tubules and maintains the secondary sexual characteristics Adrenal glucocorticoid It can increase blood sugar concentration. Promote the absorption of calcium and phosphorus in human and animal intestines
Regulate hormone levels
The biggest function of phytosterol is the hormone like function of "intelligent management". It can show certain hormone activity in the body, but has no side effects of hormones. When the human hormone level is higher than the normal value, phytosterol will "work", showing its role in hindering the absorption of bile hormones, reducing the human hormone level. When the human hormone level is lower than the normal value, Phytosterol will be "transformed" into all hormones in the human body, improving the level of human hormones, so as to achieve balance. Common phytosterols include fructus trichosanthis (commonly known as hanging melon seeds), etc. Regulate human hormone level, and have special effects in anti-aging and other aspects [4]