We work across multiple therapeutic areas to uncover biological insights to drive the discovery and development of the next generation of medicines. From the inception of a therapeutic through early clinical development, our disease area teams collaborate across scientific disciplines and organizations in support of our mission to improve and extend peoples’ lives.
Heart muscle cells.

Cardiovascular and metabolic diseases

Our Cardiovascular & Metabolic Diseases team works to better understand the root causes of cardiovascular and metabolic diseases, and discover and develop therapies against relevant targets.
Learn more
Skeletal Mitochondria

Diseases of aging and regenerative medicine (DARe)

The DARe group is focused on elucidating and targeting the molecular mechanisms underlying diseases of aging and developing potential regenerative pharmacological interventions that restore tissue integrity and function.
Learn more
Liver cells

Exploratory disease research (DAx)

DAx catalyzes and drives transformative therapies for emerging, high-potential indications. Current research focuses on liver and kidney diseases, and fibrosis.
Learn more
Novartis Institute for Tropical Diseases

Global health

The Global Health Disease Area (DA) is discovering novel medicines to help control and, ideally, eliminate diseases impacting some of the world’s most vulnerable and underserved populations.
Learn more
Multiplex immunofluorescence staining illustrating intradermal sheets of migrating stratified squamous epithelium and associated inflammatory response in Hidradenitis suppurativa.

Immunology

The Immunology group is developing transformative therapies, including small molecules and biotherapeutics, that target the root cause of disease by modulating the immune system to restore health.
Learn more
Astrocytes in a brain organoid.

Neuroscience

Our neuroscience research team works to discover transformative therapies that address the underlying cause of neurodegenerative, neurodevelopmental and neuropsychiatric diseases to dramatically improve the lives of patients.
Learn more
Breast cancer cells.

Oncology

Our Oncology team is developing a robust portfolio of treatments that destroy tumors selectively and strip away their defenses.
Learn more