Enzymes catalyzing the reversible mutual transformation of fumaric acid+H2O → L-malic acid
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Fumarase（Fumarase）The official name of fumarase is fumarate hydra tase, which catalyzes fumarate+H2O →L-malic acidEC 4.2.1.2. The optimal pH of the enzyme that can reversibly perform mutual transformation reaction is 6.5-8.0.
Chinese name
Fumarase
Foreign name
fumarase
Alias
Fumarase
Features
Catalytic fumaric acid
The substrate specificity is very strict, and the reaction balance is on the right. It is widely found in the biological world. It can be purified from liver, cardiac muscle and skeletal muscle. The molecular weight of crystalline fumarase purified from cardiac muscle is about 200000. It is composed of four polypeptide subunitsTricarboxylic acid cycleAnd therefore exists in the basic structure of mitochondria
