synonymHBsAg(HBsAg) generally refers to hepatitis B surface antigen
Hepatitis B virus shell part containssurface antigen Namely HBsAg (term:Hepatitis B surface antigen）The core part contains the core antigen HBcAg, and the e antigen HBEAg（Medical terminology：Hepatitis B E antigen）And hepatitis B virusDeoxyribonucleic acidI.eHBV-DNA、Deoxyribonucleic acidPolymeraseNamely, DNA-P.Human infection with hepatitis BVirusesAfter that, a large number of surface antigens are often left in the blood to form surface antigensHematemia。The surface antigen itself is not a complete hepatitis B virus, but the shell of hepatitis B virus. It does notinfectivityBut there areantigenicityIt is only one of the signs of hepatitis B virus infection.It can indicate that you have been infected with hepatitis B virus in the past, or you are being infected with hepatitis B virus.
The 2008 edition of the Guidelines for the Treatment of Chronic Hepatitis B issued by the Asia Pacific Society for Liver Research pointed out that China is a high prevalence area of hepatitis B virus infection,Hepatitis B virus surface antigenThe total number of people carried has exceeded 100 million, including chronicHepatitis B patientsMore than 20 million people, accounting forTotal populationAbout 1.6%.
Normal value
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hepatopathyAccording to experts, in different hospitals, hepatitis B surface antigenNormal valueThe scope will be very different.The normal range of HBsAg is expressed in different ways, and its value is also different.The normal value of HBsAg can be expressed in the following ways:
1、ng/mlRepresentation。If the normal value of hepatitis B surface antigen (ng/ml) is greater than 0.18ng/ml, it means that there is hepatitis B virus in the patient, and hepatitis B surface antigen is considered as a positive result, otherwise it is considered as a negative result.
2. S/CO value representation.If the normal value of hepatitis B surface antigen (S/CO) is greater than 1S/CO, it means that the patient has hepatitis B virus in his body, and hepatitis B surface antigen is considered as a positive result, otherwise it is considered as a negative result.
3、S/NValue representation.AXSYMImmune analyzerThe S/N value is obtained. If the normal value of hepatitis B surface antigen (S/N) is greater than 2.1S/N, it means that the patient has hepatitis B virus in his body, and hepatitis B surface antigen is considered as a positive result, otherwise it is considered as a negative result.
Can the positive change to negative
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(1) Most adults infected with hepatitis B virus will automatically turn negative: most adults infected with hepatitis B virus areAcute hepatitis B(within half a year of infection),Acute infectionMost (90%) will self heal, that is, within 3 monthssurface antigen The positive turns to negative and produces surface antibody, and the other 10%, such asimmunityPoor, not enoughhepatitis B surface antibodyTo neutralize the surface antigen, HBsAg in serum can be continuously positive;That is to say, it becomes chronicHBV carriers。Therefore, it is suggested that adults with negative antibodies should also be injectedhepatitis B vaccine。
(2) 1-5% of chronic hepatitis B carriers can turn negative with surface antigen every year: chronicHepatitis B carriersMost of them are infected when the immune system is immature, so the immune system fails to recognizeVirusesAnd become a carrier of hepatitis B.When HBV carriers are infected in childhood, most of them are“hha ”At this timeimmune toleranceThe status virus and the body are relatively stable and will not get sick. With age, the immune system gradually recovers by 50% and can gradually become“Xiao Sanyang”(e antigen negative), 1% of which can completely eliminate the positive virus surface antigen to negative.
HBsAg negative
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Hepatitis B surface antigen (HBsAg) is the coat protein of hepatitis B virus, which is not infectious, but its appearance is often accompanied by the existence of hepatitis B virus, so it is a sign of infected hepatitis B virus.It can exist in the patient's blood, saliva, milksweat, tearsnasopharynxSecretions, semen andVaginal dischargeMedium.Two to six months after infection with hepatitis B virus, whenAlanine aminotransferasePositive results can be detected in serum 2 to 8 weeks before the elevation.A positive HBsAg can only indicate that the person is infected with HBV, but it cannot be determined whether the person is infectious.If it is necessary to determine whether the hepatitis B virus in the patient is infectious[1]Other items should also be tested.
Negative conversion of hepatitis B surface antigen means that hepatitis B is cured and will not be infected again, which means that the patient has basically got rid of hepatitis B disease, but it needs lifelong monitoring when getting hepatitis B. Even if the hepatitis B surface antigen (HBsAg) has turned negative, you cannot relax your vigilance.To maintain for a long time, doctors and patients need to work together.As long as we pay attention to our living habits, diet and exercise in the future, hepatitis B will not recur.
Will HBsAb disappear
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Whenhepatitis BWhen the virus invades the human body, it will stimulate peopleimmune systemproduceimmune reaction, B in the body's immune systemCellsWill secrete a special human bodyimmunoglobulin, namely surface antibody, which can interact with hepatitis B surface antigenSpecific bindingThen, under the function of the body and other immune capabilities of the human body, it can clean up the hepatitis B virus and protect the human body from being infected by the hepatitis B virus at the same time.The presence of surface antibodies proves that people have developed immunity, such ashepatitis B surface antibodyPositive results, it means no infection with hepatitis B.
So,Can hepatitis B surface antibody disappear?
It is undeniable that,HBsAb will gradually decrease or disappear over time, therefore, in order to maintainhepatitis B antibodyTo exist continuously and effectively, it is necessary toRegular inspectionHBsAb status and strengthen vaccination every 3-4 yearshepatitis B vaccine。
Antigen positive and marriage relationship
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Patients with positive hepatitis B surface antigen can get married
hepatitis BThe surface antigen itself does not haveinfectivityTherefore, it should not be regarded as a sign of infectivity.But generally speaking, HBsAg is positivehepatitis B virusThe presence of other markers of hepatitis B virus indicates that the person's blood is carrying or has hepatitis B virus replication.Therefore, it is better to check hepatitis B virus markers before marriage for hepatitis B surface antigen positive persons and their subjects.If the surface antibody in the other party's blood is positive, it means that the other party has immunity to hepatitis B virus and is not easy to be infected again, and can get married.If the other party's hepatitis B signs are all negative, it means that the other party has neither been infected with nor immune to hepatitis B virus, and is susceptible to infection after marriage, so it is not suitable for marriage temporarily.Inject according to the "0, 1, 6" schemehepatitis B vaccine。It may be safer to wait 6 months before getting married when enough protective antibodies are produced in the body.
Hepatitis B diet
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The diet of hepatitis B patients should be avoidedSpicy food, becausehot food Can cause digestive tract of patientsdysfunctionThe digestive function of the patient is weakened.
smokeIt is also necessary for hepatitis B patients to quit in their daily life, because tobaccoOil wearinessMultifariousToxic Substances, can cause liver function damageHepatocyteThe repair and regeneration of is unfavorable.
AlcoholIt is a must for hepatitis B patients to abstain from life, because most alcohol is metabolized through the liver, which will damage liver cells and cause necrosis of liver cells. Therefore, patients with liver disease should not drink alcohol, even a small amount of alcohol will cause recurrent attacks of liver disease.
Don't eatProcessed foodThe reason why patients with hepatitis B should not eat processed food is that these foods are addedpreservativeIt is toxic to the liver and is not conducive to the recovery of the disease.
Patients with hepatitis B should avoidTaking antibiotics and stimulatingThe drug is toxic to the liver, so patients with hepatitis B should use it reasonably with the knowledge of doctors.
Patients with hepatitis B shouldAvoid misusing supplementsFor patients with liver disease, a reasonable diet is helpful for their condition, but misuse of supplements will lead to improper nourishing, which will lead to liver dysfunction and be detrimental to the recovery of the body.
Seven Taboos of Diet for Patients with Hepatitis B: Excessive UseHigh protein dietAnd high copper diet, which is mainly because eating more of these foods will cause hepatitis B patients with poor digestive functionindigestionandabdominal distentionAnd other symptoms.
