Gene is the material basis of heredity, which determines the biological characteristics of pathogens.Except for a few viruses, all known microorganisms use nucleic acid as genetic material.The gene of hepatitis B virus is deoxyribonucleic acid (DNA), which is closely related to DNA polymerase necessary for virus replication.Therefore, gene detection has become an integral part of hepatitis B detection.
(1) Elevated: In patients with persistent hepatitis B virus infection, acute hepatitis B incubation period, initial stage, reproductive period, chronic hepatitis B, positive e antibody of chronic hepatitis B, and high value of DNA polymerase, liver function deteriorates.(2) Decrease: e antigen positive patients with chronic hepatitis b.
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(1) The activity of this enzyme can be detected in the early stage of hepatitis B virus infection, even before the emergence of HBsAg.(2) It can be used as a sign of hepatitis B virus replication and infectivity.
