Degenerative osteoarthropathy

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Disease name
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synonym Osteoarthritis (Osteoarthritis) generally refers to degenerative osteoarthritis
Kong Qingquan Chief physician (written) Department of Orthopaedics, West China Hospital, Sichuan University
Degenerative osteoarthropathy is also called bone arthritis , degenerative arthritis, senile arthritis hypertrophy Sexual arthritis is a kind of Degenerative lesion , due to aging, obesity strain , trauma, congenital abnormality of joints Joint deformity And many other factors Articular cartilage Degenerative injury, reactive hyperplasia of articular margin and subchondral bone. This disease is mostly seen in the middle-aged and elderly people, and tends to occur in load-bearing joints and joints with more activities (such as cervical vertebra, lumbar vertebra Knee joint hip joint Etc.). Excessive weight bearing or the use of these joints can promote Degenerative change Occurrence of. The clinical manifestation is slow development Arthralgia , tenderness, stiffness, joint swelling Restricted activity And joint deformity.
Foreign name
degenerative osteoarthrosis
Alias
Osteoarthritis Degenerative arthritis Senile arthritis Hypertrophic arthritis
Visiting department
orthopaedics
Common causes
Unknown
common symptom
Joint pain, often rest pain, joint stiffness
Chinese name
Degenerative osteoarthropathy

pathogeny

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The etiology is still unclear, which may be related to the elderly, women, obesity, occupational overuse and other factors.

clinical manifestation

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The main symptoms are Arthralgia It is often a pain at rest, which is manifested as pain after rest and will be relieved after a moment of activity, but the pain will be aggravated after too much activity. Another symptom is Joint stiffness It often occurs when getting up in the morning or after the joints have been in a certain position for a long time in the daytime. Swelling and tenderness of the affected joint can be seen through inspection, and there is a sense of friction or "clicking" sound during the activity, which can occur in serious cases Muscular atrophy and Joint deformity [2]
Anatomical example [2]

inspect

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Imaging inspect
  1. one
    X-ray films showed unequal width or narrowing of joint space, osteoporosis, hyperosteogeny or joint enlargement at joints, and even joint deformation, subchondral bone plate sclerosis and osteophyte formation.
  2. two
    CT can clearly show different degrees of joint bone hyperplasia, intra-articular calcification and free bodies, and sometimes the meniscus.
Blood cell sedimentation rate Hemogram No abnormal change, thermal agglutination test Positive. Articular fluid is usually clear Yellowish Viscosity High, White blood cell count Usually 1.0 × 10 nine /Within L, mainly monocyte Mucin The clot is firm.

diagnosis

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According to relevant medical history, clinical manifestations and X-ray It is not difficult to diagnose degenerative osteoarthropathy. Joint synovial fluid can be checked if necessary.

treatment

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The main treatment of degenerative osteoarthropathy is to reduce the weight bearing and excessive large range of activities of the joint to delay the process of the disease. Obese patients should reduce weight and joint load. Crutches or crutches can be used when the joints of lower limbs are diseased in order to reduce the burden on the joints. physiotherapy And proper exercise can keep joint Scope of activities , splint can be used if necessary Brace And walking stick, etc acute stage The symptoms are helpful. Antiinflammatory and analgesic drugs can reduce or control symptoms, but patients should be evaluated risk factor After that, it should be used carefully and should not be taken for a long time. cartilage Protective agent as Glucosamine sulfate It can alleviate symptoms and improve functions, and long-term use can delay the structural progress of the disease. For late cases, if the general condition can tolerate surgery Artificial joint replacement It is recognized as an effective method to eliminate pain, correct deformity and improve function, which can greatly improve patients' Quality of life [1]