Magnesium is necessary for human bodyMineral elementBecause the content of magnesium in human body is high, it is calledConstant element。The total content of magnesium in normal adults is about 25g, of which 60% - 65% is in bone and teeth, and 27% is in soft tissue.Magnesium is mainly distributed in cells,Extracellular fluidNot more than 1% of magnesium.Its main physiological functions are: activating the activities of various enzymes in the human body;Maintain bone growth and neuromuscular excitability;Maintain the function of gastrointestinal tract and hormone.If magnesium is deficient, the above functions will be affected, which may lead toSerum calciumDecline;Neuromuscular hyperexcitability;Potential impact on vascular function (reported by someone)HypomagnesemiaPatient can have roomVentricular premature beat，atrial fibrillationas well asVentricular tachycardiaAnd ventricular fibrillation, half of them had elevated blood pressure;ProbablymenopausePost womenOsteoporosisA risk factor of;There are also studies that show that magnesium depletion can lead toinsulin resistance Related to diabetes).Magnesium is rich in coarse grains, green leafy vegetables and nuts, while the content of magnesium in meat, starch foods and milk is medium.
A Japanese research team in the new issue of the United States《neuron》The magazine reported that they usedDrosophila melanogasterExperiments show that magnesium ion can block the production of an inhibitory protein in nerve cells, thus helping maintainlong-term memory 。
Previous studies have shown that NMDA glutamate receptors in the central nervous system play an important role in learning and memory.This receptor absorbsglutamateAfter that, the nerve cells will absorbcalcium ionAnd trigger biochemical reactions necessary for learning and memory.however,calcium ion channelsIt is usually blocked by magnesium ion. Only when the nerve cell is activated and becomes excited, magnesium ion will leave, and calcium ion can enter the nerve cell.
Researchers believe that the blocking effect of magnesium ion can prevent excessive calcium ions from entering nerve cells and prevent the increase of inhibitory CREB protein.This discovery is expected to promote the discovery that aging causesMemory declineAndAlzheimer diseaseAnd so on.
