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Metalloprotein

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Metal containing protein
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Metalloprotein, composed of protein and metal ion Combination formation. Most of the metal ions are only associated with proteins connect ； A few are connected with a smaller molecule Connected, such as hemoglobin In iron (II) In addition to connecting with protein porphyrin to be connected. Metalloprotein Important physiology Function. If hemoglobin is transported oxygen Required. Ceruloplasmin can catalysis Ferruginous oxidation In favor of iron (III) and protein Syngenetic formation Transferrin 。 Transferrin for transport Iron. ferritin For Storage Iron, etc.
Chinese name
Metalloprotein
Foreign name
metalloprotein
Composition
protein and metal ion
Category
Ferritin ， Ceruloplasmin ， Ferrithionein etc.
type
Class I contains metallic element Of protein , there are mainly the following types:
(1) Ferritin 。 as hemoglobin 、 myoglobin 、 Cytochrome The first two have Oxygen carrying 、 Oxygen storage Function, Cytochrome C yes Electron transmitter 。
(2) Ceruloplasmin , i.e Cupric protein , such as plasma Cyanin and Plastochrome , the former participates organism within copper The latter is Biological process Electrons in Transferor 。
(3) Ferrithionein , is a class of iron sulfur Natural Atomic cluster Metal compound On the protein chain Cysteine Combined Metalloprotein , such as bacteria Ferredoxin Including Fe4S4 Atomic cluster , it is organism It is an important electron transmitter.
(4) Metalloenzyme 。 With catalysis in organism chemical reaction Metalloprotein, often metal Ions be located activity Center, such as Zinc enzyme ( Carboxypeptidase and carbonic anhydrase )。
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