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Transformed cell

Cell type
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Cell transformation is a change in the genetic character of cells, which is based on DNA or gene mutation.
Chinese name
Transformed cell
Foreign name
transformed cell
Approach
Cytogenetic changes
Foundation
Mutations in DNA or genes
Purpose
Transformation of organisms caused by gene mutation
In terms of attributes, gene mutation leads to the transformation of organisms, which is beneficial to the transformation of organisms, but also detrimental to the transformation of organisms (such as canceration). Cells cultured in vitro are exposed to Mutagenicity The transformation can take place when the DNA (gene) structure changes. All factors that can induce DNA (gene) structure changes are regarded as inducing factors, including physical factors (such as radiation), chemical factors (MNNG), viruses (EBV, SV40), and oncogenes, but they need the help of vectors and auxiliary factors. Without any mutagenic treatment, the spontaneous transformation of cells is SPONTANEOUS TRANSFORMATION. When cells co-exist or are subcultured repeatedly, it can occur under the influence of some factors that are difficult to control, such as serum quality decline, virus pollution, temperature and pH fluctuations, and cells are sensitive to the external environment.