Iron is an essential element for the formation of heme, which is the raw material for the synthesis of hemoglobin and myoglobin, and also an essential substance for promoting the metabolism of B vitamins.Serum iron is the amount of iron bound to transferrin in the blood.Under normal circumstances, the bivalent iron entering the blood from the small intestine is oxidized into trivalent iron in the blood. The trivalent iron is combined with plasma transferrin and transported to bone marrow or other iron demanding tissues for utilization.
Chinese name
Serum iron
Male
11~30 umol/L
essence
Transferrin iron binding, called serum iron
female sex
9~27umol/L
atlas
Science popularization in China
Committed to authoritative science communication
The certification expert of this term is
Yang Tiesheng|Chief physician
Laboratory Department of Peking University People's Hospitalto examine
It is mainly found in sideroblastic anemia, chronic hemolytic anemia, severe liver disease and hemochromatosis.In acute liver cell damage, such as acute severe hepatitis, the serum iron content increases due to the release of iron stored in the liver to the blood.In hemolytic anemia, because a large number of iron in red blood cells enter the blood stream, serum iron can also be increased.In addition, when the utilization rate of iron in the body is reduced, invalid red blood cells are generated, accompanied by increased destruction of bone marrow red blood cells, such as aplastic anemia, sideroblastic anemia, thalassemia and chronic hemolysis, or the serum iron content is often increased in lead poisoning.Patients who received repeated blood transfusion and iron treatment were often higher.
2. Pathological decrease
The serum iron content is normal or below the normal level in patients with long-term severe infection, malignant tumor, liver cirrhosis and obstructive jaundice.Therefore, serum iron is very valuable in distinguishing hepatocellular jaundice from obstructive jaundice.Insufficient total iron in the body, such as malnutrition, gastrointestinal diseases, peptic ulcer, chronic diarrhea, etc., will cause a decrease in serum iron.In addition, the need for iron in the body increases, such as pregnancy, infant growth period, etc., and there is also a tendency to reduce serum iron.
Normal value reference range
Announce
edit
1. Healthy adults
(1) Male: 10.7 ～ 29.5 μ mol/L
(2) Female: 9.1~26.5 μ mol/L
2. Infants
(1) Newborn: 18 ～ 45 μ mol/L
(2) Infants: 7-18 μ mol/L
(3) Children: 9 ～ 22 μ mol/L
3. Elderly
7.2～14.3μmol/L
matters needing attention
Announce
edit
1. Avoid hemolysis of the sample.
2. Aspirin, coelenamine and glucocorticoid can reduce the results.Dextran, oral contraceptives and iron can increase the test results.Therefore, oral administration of such drugs should be avoided before blood drawing.
3. The serum iron content fluctuates day and night. It is the highest in the morning, then gradually decreases, and the lowest at midnight. Therefore, it is better to conduct the sample at a fixed time.
