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Sodium deoxycholate

chemical substances

white Crystallinity Powder. similar bile Smell. It has a strong bitter taste. Easy to absorb moisture. Easily soluble in water, slightly soluble in anhydrous alcohol, insoluble in ether 。 Specific rotation About+42.5 º (c=2, in water). Low toxicity, Median lethal dose （ Rat , oral) 1370mg/kg. Irritating.

Chinese name: Sodium deoxycholate^[1]
Foreign name: Sodium deoxycholate^[1]
Alias: Sodium 3 α, 12 α - dihydroxy-5 β - cholanate^[1] ; Deoxycholic acid sodium
CAS No: 302-95-4^[1]
Molecular formula: C24H39O4Na

molecular weight: four hundred and fourteen point five five
Purity: >99%
MDL No: MFCD00064139
Beilstein: three million five hundred and eighty-one thousand nine hundred and fifty
EC No: 206-132-7^[1]

catalog

seven purpose

English alias

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3α,12α-Dihydroxy-5β-cholanic acid sodium salt, 7-Deoxycholic acid sodium salt, Desoxycholic acid sodium salt

Sodium desoxycholate; 3-alpha,12-alpha-Dihydroxy-5-beta-cholan-24-oic acid sodium salt; CCRIS 655; Deoxycholate sodium; Deoxycholic acid sodium salt; Desoxycholate sodium; Dihydroxy 3-12 cholanate de Na; Dihydroxy 3-12 cholanate de Na [French]; Na-Desoxycholat; Na-Desoxycholat [German]; Natrium-3-alpha,12-alpha-dihydroxycholanat; Natrium-3-alpha,12-alpha-dihydroxycholanat [German]; Sodium 7-deoxycholate; Sodium deoxycholate; Sodium deoxycholic acid; UNII-436LS6U35Y; 3,12-Dihydroxy-cholan-24-oic acid monosodium salt, (3-alpha,5-beta,12-alpha)- (9CI); 5-beta-Cholan-24-oic acid, 3-alpha,12-alpha-dihydroxy-, sodium salt; Cholan-24-oic acid, 3,12-dihydroxy-, monosodium salt, (3-alpha,5-beta,12-alpha)- (9CI); Cholan-24-oic acid, 3,12-dihydroxy-, monosodium salt, (3alpha,5beta,12alpha)-; Deoxycholic acid, sodium salt; Sodium 3-alpha,12-alpha-dihydroxy-5-beta-cholan-24-oate; sodium (3alpha,5beta,12alpha)-3,12-dihydroxycholan-24-oate; cholan-24-oic acid, 3-hydroxy-, monosodium salt, (3alpha,5beta)-; oxoniomethyl

character

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Melting point: 357-365 º C^[1]

Water solubility : 330G/L(15ºC)

Specific rotation : 44º(C=2, H2O )

Safety terminology

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S22Do not breathe dust.

Do not breathe dust.

Risk terminology

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R22Harmful if swallowed.

Harmful if swallowed.

quality standard

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project Biological reagent level

arsenic Arsenic(%) ≤0.001

Heavy Metals (%) ≤ 0.005

Loss on Drying (%) ≤ 5.0

Purity (Dry Basis) (%)>99.0

Sodium cholate Sodium Cholate(%) ≤2.0

Solubility (10%, Water) (P/F) is qualified

Structural formula of sodium deoxycholate

keep in storage

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Room temperature storage

purpose

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Preparation of bacteria culture medium , instead of Cephalin do cholesterol Flocculation test, protein analysis.

Effect of sodium deoxycholate and sodium orthoaluminate in pyrolysis solution

The former is ionic Detergent , the latter is inhibition Tyrosine phosphatase Active.

The main functions of ionic detergent include: 1. lysis of cells; 2. Dissolve proteins, especially some proteins that are difficult to dissolve in water, such as Membrane protein Etc; 3. It is suitable for WB, but it should be used carefully in Co IP.

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