abbreviationchronic nephritis , referring to proteinuria, hematuria, hypertension and edemaclinical manifestation, the way of onset is different, the condition is prolonged, the disease progresses slowly, and may have different degreesrenal functionDecline and eventually develop intochronic renal failure A group ofGlomerulopathy。Due to the different pathological types and stages of the diseases in this group, the main clinical manifestations are different, and the disease manifestations are diversified.
It is a group of clinical syndromes characterized by tubular atrophy, infiltration of inflammatory cells in the renal interstitium and fibrosis.The mechanism of renal interstitial damage may involvegenetic, Immunizationrelevance、Infectivity、Blood system diseases, poisoningMetabolic disorder, urinary mechanical obstruction andrenal transplantExclusion and other factors.The clinical manifestations are different degrees of renal tubular dysfunction and progressive chronic renal failure.
abbreviationHepatitis B associated nephritis, is byChronic hepatitis BAfter the virus (HBV) infects the human bodyImmune complexnatureGlomerulopathy。The clinical manifestations vary in severity, which can be manifested as asymptomatic urine test abnormalities ornephropathyThe range of proteinuria may be accompanied by hematuria of different degrees.Kidney damageThe pathological types are diverse, and childrenMembranous nephropathyIt is common in adults and can be manifested as membranous proliferative nephritis or membranous nephropathy.
It refers to the clinical manifestation ofreversibilityNon oliguria acute renal injury, tubulointerstitial disease of unknown etiology.Renal pathology shows interstitial edema and mononuclear cell infiltration, but it is difficult to determine the specific cause clinically.Most of them are related to autoimmune diseases, and some patients can finally be identified by close monitoring and dynamic observation.As withChronic active hepatitis、Ulcerative colitis、Autoimmune thyroid diseaseAnd so on.TINU syndrome is one of the special typesUveitis, which may occur before kidney damage (several weeks), at the same time or after kidney damage (several weeks to several months).It is common in children, adolescents or adult women.
Urine examination: proteinuria, hematuria, tubular urine, leucocynuria, pyuria and bacteriuria.
two
Determination of glomerular filtration rate
three
Blood creatinine and blood urea nitrogen were detected.
four
Serum complement C3, C4 and CH50;Serum anti streptolysin "O" titer;Anti nuclear antibody spectrum, ENA polypeptide antibody spectrum, immunoglobulin, ANCA, anti glomerular basement membrane antibody, etc.
Including avoiding fatigue, removing infection and other incentives, and avoiding contactNephrotoxicityDrugs or poisons, adopt a healthy lifestyle (such as quitting smokingModerate exerciseAnd emotional control) and reasonable diet.acute stageStay in bed and rest, and gradually increase the amount of activity after the clinical symptoms improve.In acute phaseLow salt diet(less than 3g per day).Not required for people with normal renal functionRestriction proteinQuality input, butAzotemiaProtein intake should be limited and high qualityanimal protein Mainly.People with oliguria should limit their fluid intake.
Kidney disease patients often have a variety of complications, such as metabolic abnormalities, hypertensioncoronary heart disease、heart failureandcirrhosisIt may aggravate the progress of kidney disease and should be actively treated.
