Department of Gastroenterology, General Hospital of Beijing Military Region
Hepatitis is a general term for liver inflammation.Usually refers to multiple pathogenic factors such asViruses, bacteriaparasite, chemical poisons, drugs, alcoholAutoimmunityFactors such as liver cell damage, liver function damage, and a series of uncomfortable symptoms of the body, andliver functionThe indicator is abnormal.
Although there are similar causes of hepatitisclinical manifestation, but inEtiology、serology, injury mechanism, clinical process andprognosis, extrahepatic damage, diagnosis and treatment are often significantly different.
It should be noted that most of the so-called hepatitis in our life refers to hepatitis A, hepatitis B, hepatitis C, etchepatitis virusCaused byViral hepatitis。
The increase of unexplained childhood hepatitis cases since 2022 is related to adeno-associated virus type II (AAV2), a common childhood virus。[9]
TCM disease name
hepatitis
Foreign name
Hepatitis
Visiting department
Infection Department, Hepatitis Department, Digestive Department
Common causes
Caused by viruses, bacteria, parasites, drugs, alcohol and other factors
common symptom
Loss of appetite, abdominal distension, aversion to greasy food, nausea, vomiting, and fatigue
infectivity
yes
Route of transmission
Viral hepatitis is infectious and can be transmitted through contact in daily life, blood borne transmission, mother to child transmission, iatrogenic transmission and sexual contact
It has great value in the diagnosis of various types of hepatitis. It can be scored by liver tissue electron microscopy, immunohistochemistry and Knodell HAISystematic observation, correct data can be obtained on the etiology, etiology, inflammatory activity and fibrosis degree of hepatitis, which is beneficial toclinical diagnosisAnd differential diagnosis.
diagnosis
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According to the medical history, clinical manifestations and examination results.
treatment
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According to the etiology, course and severity of hepatitis, different treatment principles and measures should be taken.
In April 2022, Britain, SpainIrelandThe United States reported that hepatitis cases with unknown etiology were found among children, and new coronavirus was detected in some casesVirusesoradenovirus。However, these viruses are found in hepatitis casesPathogenesisThe role of is unclear.[1]
On April 28, 2022, three cases were found in Japan.Ministry of Health of SingaporeA 10 month old boy was reported to have similar symptoms.
On May 6, 2022, the U.S. Centers for Disease Control and Prevention said that 109 children with unknown causes have been reported in the United StatesAcute hepatitisCases, 5 of them died.The agency is investigating the cause of these cases. So far, there is no evidence that these children's hepatitis cases are associated with new coronavirus infection or vaccinationNew coronal vaccineof[3]
On May 10, 2022, the South Korean Central Anti epidemic Countermeasures Headquarters said that on May 1, South Korea reported a suspected case of acute hepatitis in children with unknown causes.[4]
May 10, 2022 local time, CanadaTorontoAccording to the Children's Hospital, there have been 7 cases of severe acute hepatitis with unknown causes.The hospital said the cases were of "unknown origin".[5]
On May 10, 2022,Swedenpublichealth bureauSaid that up to now, there have been 9 cases of acute hepatitis in children with unknown etiology in Sweden, and the bureau urged medical staff to treat these suspected diseasesBe alert.[7]
May 12, 2022, Deputy Governor of Jakarta, IndonesiaAhmed Riza PatriaAccording to the introduction, the local government recorded 21 cases of acute hepatitis with unknown causes, 14 of which were children under the age of 16.He said: "In 21 cases, 3 people have died." It is understood that 21 cases of suspected acute hepatitis of unknown cause found in Indonesia have no history of traveling abroad.[6]
2022 to 2023In April,More than 1000 cases of unexplained childhood hepatitis have been reported in 35 countries, including Britain and the United States.Three independent studies have pointed out that the increase of unexplained childhood hepatitis cases since 2022 is related to adeno-associated virus type II (AAV2), a common childhood virus。[9]
Prevention of hepatitis
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Prevention of hepatitis E virus[8]
(1) Pregnant women should be vaccinated half a year in advanceHepatitis E vaccine。
(3) Isolation treatmentHepatitis Epatient.Temporary isolation points should be set up to treat early patients.
(4)Close contacts(Eat, live, live together or contact frequently with hepatitis E patientsHEVFor those who do not take protective measures for pollutants), it shall be implemented for 60 days from the last contactMedical observation。