Liver injury

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Li Bin Associate chief physician (review) Tangshan People's Hospital Hepatobiliary Surgery Department
The liver is the largest in the abdominal cavity Substantive Organs are important to the human body physiological function Hepatocyte Anoxic Tolerance Poor, so hepatic artery and portal vein It provides abundant blood supply and has large and small bile duct Accompanying with blood vessels bile It is located deep in the right upper abdomen, with the lower chest wall and Diaphragm Protection of. However, due to the large size and fragile texture of the liver, once subjected to violence, it is easy to damage the abdominal cavity Internal hemorrhage Or bile leakage Hemorrhagic shock or Bile peritonitis The consequences are serious and must be diagnosed and handled correctly in time.
Foreign name
liverdamage
Visiting department
Surgery
Common causes
Knife stab injury, firearm injury, impact, extrusion
common symptom
Hypovolemic shock, peritonitis

pathogeny

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According to the cause of injury, liver trauma is generally divided into Open injury And closed injury. Open injuries generally include stab wounds Firearm wound Etc. The stab wound is relatively minor, Case fatality rate Low. Firearm injuries are open injuries caused by projectiles launched by gunpowder War wound See more in, Liver fire Gun wound is the most common type of abdominal firearm wound. Open injury can be divided into blind tube injury and Penetrating wound Two. Closed abdominal injuries are mostly blunt injuries, which are mainly caused by impact and extrusion, and are common on highways traffic accident Building collapse, occasionally seen in falls, sports injuries or beatings.
Because closed abdominal injury is often accompanied by other organ injuries except liver trauma, and there is no sign of injury on the surface of the abdomen, it is relatively difficult to diagnose, leading to delayed treatment Blunt injury It is dangerous, and the case fatality rate is often higher than that of open injury.

clinical manifestation

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Liver trauma The patient usually has a clear right chest and abdomen History of trauma , thirst, nausea and vomiting. Mainly Hypovolemic shock and peritonitis Some patients with liver trauma have massive abdominal bleeding, which can also occur abdominal distention Etc. Due to different causes of injury, Hepatic trauma Of clinical manifestation It is also inconsistent.
Hepatic capsule lower hematoma Or small hematoma in the liver parenchyma, mainly in the liver region clinically Dull pain , visible through physical examination Hepatomegaly Or upper Abdominal mass If the hematoma is connected to the biliary tract, it will be Biliary hemorrhage , causing Upper gastrointestinal bleeding , long-term repeated bleeding can lead to chronic progressive anemia If the bleeding in the hematoma continues to increase and the tension of the liver capsule is too large External force action Sudden rupture of the lower part, acute Hemorrhagic shock Therefore, for patients with subcapsular hematoma surgical treatment We must pay attention to the possibility of delayed bleeding. If hematoma Secondary infection , can appear shiver High fever , pain in liver area, etc Liver abscess Of sign
In case of superficial liver laceration bile Extravasation Not much, and in a short time Internal hemorrhage It can stop by itself. Generally, it only has pain in the right upper abdomen, and rarely has shock and peritonitis.
Central type Hepatic rupture or Openness Liver injury The liver tissue is widely fragmented, generally involving large blood vessels and bile duct Abdominal hemorrhage and bile extravasation are frequent, and patients with liver trauma often have acute shock symptoms and the peritoneum Irritating symptoms. It is characterized by abdominal pain, pale face, fine pulse, and decreased blood pressure, Urine output Reduction, etc. Abdominal tenderness Obviously, Abdominal muscle tension With the increase of bleeding, the above symptoms are further aggravated.
Severe liver fragmentation or combination Hilum hepatis nearby Large blood vessel In case of rupture, such as portal vein Inferior vena cava And so on, which may cause uncontrollable massive bleeding. large Vascular injury Can lead to a large number of Power The fatal hypovolemic shock caused by blood loss often dies in the process of treatment and loses the opportunity of surgical treatment.

inspect

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There was no obvious change in the early stage of mild liver trauma. Because of the rapid loss of blood, Blood concentration , many patients do not appear hemoglobin But in patients with liver trauma White blood cell count Can be raised.
(1) Abdominal puncture For diagnosis of abdominal visceral rupture, especially for Substantive Organ laceration is of great value. Generally speaking, it can be considered that there is Visceral injury But it may be false when the amount of bleeding is small Negative results Therefore, a negative puncture cannot exclude visceral injury. If necessary, multiple punctures at different locations and at different times, or diagnostic lavage of the abdominal cavity shall be performed to help diagnosis.
(2) Timing measurement red blood cell , hemoglobin and Hematocrit Observe the dynamic changes. If there is progressive anemia, it indicates internal bleeding.
(3) B-mode ultrasonic examination Not only can we find Hematocele It is also helpful for the diagnosis of hepatic subcapsular hematoma and intrahepatic hematoma, which is commonly used clinically.
(4) X-ray If there is subcapsular hematoma or intrahepatic hematoma, X-ray photography Or the liver shadow can be enlarged and Diaphragm raise. as At the same time yes Free gas downstream of diaphragm , you will be prompted to merge cavities visceral organ injury
(5) Liver radioactivity The diagnosis of radionuclide scanning is not clear Closed injury If there is a suspected subcapsular or intrahepatic hematoma, the injury is not very urgent, and the patient's condition allows isotope Liver scan. Those with haematoma showed radioactive defect area in liver.
(6) Hepatic arteriography For some closed injuries that are really difficult to diagnose, such as suspected intrahepatic hematoma, this method can be used if the injury is not very urgent. Branches of intrahepatic artery can be seen aneurysm Formed or contrast agent Spillover and other signs of diagnostic significance. It cannot be used as a routine inspection.

diagnosis

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It is easy to make a diagnosis of open liver injury, but attention should be paid to whether there are Combined thoracoabdominal injury Closed injury with typical hemorrhagic shock and Peritoneal irritation sign Combined with the history of trauma, it is easy to make a diagnosis. But for some Concomitant injury Of patients with liver trauma, such as Brain trauma Unconscious, Multiple fractures Those with shock, old, weak and unresponsive should be alert to avoid missed diagnosis. cirrhosis or liver cancer The patient's liver rupture can be caused by slight trauma, so it should not be taken lightly. Closed abdominal injury Whether there is liver injury is involved in the question of whether to open the abdomen accuracy High requirements. When the diagnosis is in doubt, puncture through abdominal cavity Peritoneal lavage And other auxiliary examinations can help diagnosis.

treatment

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First, consider the patient's general condition and whether there is Compound injury , such as whether there is brain, lung Bone injury The reasonable treatment plan shall be determined according to the general condition and the priorities of the combined injuries. For patients with simple liver injury, actively correct hemorrhagic shock and actively prepare for surgery.
keep respiratory tract Smooth and sufficient oxygen supply. Quickly establish more than two venous channels to ensure smooth blood transfusion and transfusion and avoid blood flow of important organs Inadequate perfusion When the patient's condition is improved and stable, make necessary checks, and make further diagnosis treatment planning In case of severe shock, blood transfusion fluid infusion Actively operate while expanding the volume.
2. Non operative treatment
Indications for non-surgical treatment:
(1) Patients with grade I, II or III hematoma (AAST classification) without active bleeding and progressive expansion of hematoma.
(2) Hemodynamics In stable cases, the amount of bleeding shall not exceed 600ml.
(3) Symptoms of peritonitis Light, the patient is conscious and can cooperate with the physical examination.
(4) No intra-abdominal injuries were found. This can be done in Dynamic monitoring Vital signs , hemoglobin Abdominal circumference In the case of, surgery is not needed temporarily.
The patient should absolutely lie in bed for more than 2 weeks, calm and relieve pain, transfusion and fluid replacement, prevent infection, and correctly use hemostatic drugs. The choice of antibiotics is based on the bacteria that may exist in bile. Hemostatic drugs shall be used in combination with anticoagulant and anti fibrinolytic drugs, and if necessary, small amount shall be used in combination vasoconstriction Agent. It is feasible for patients with abdominal distention Gastrointestinal decompression To promote gastrointestinal function functional recovery So that the blood accumulated in the abdomen can be easily absorbed. In some patients, selective hepatic arteriography can be used to find the bleeding focus and then embolize, with good results.
3. Surgical treatment
When patients with liver trauma have obvious symptoms of intraperitoneal hemorrhage, peritonitis, or abdominal organ injuries, shock should be corrected at the same time Exploratory laparotomy Operative basic principle For:
(1) Hemostasis;
(2) Ligation of bile duct;
(3) Clearing necrotic liver tissue;
(4) Drainage;
(5) Treatment of combined injuries.