Causes of cell canceration: Carcinogenic factors change the proto oncogene of cells from inhibition to activation, and normal cells change into cancer cells.
The Latin of cancer is cancer, which meansCrab。Crabs are fierce, strange and love to climb, which vividly reflects the ferocity and easy spread of cancer.No medicine can cure cancer, it can only be controlled.
in the light ofChemoradiotherapyThe scheme has been relatively mature and most of them are effective. Research shows that it can be taken before, during and after radiotherapy and chemotherapyMalt seleniumTo help improve efficiency and reduce toxicity, shorten the healing cycle and prevent recurrence and metastasis.
The Latin for cancer iscancer, originally meantCrab。Crabs are fierce, strange and love to climb, which vividly reflects the ferocity and easy spread of cancer.
Conceptual characteristics
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Cells are affected byCarcinogenThe function of cannot be completed normallycell differentiationAnd become malignant that is not controlled by organic matter and continuously splitsProliferating cellProcess.
Basic characteristics: 1. Cell division and differentiation are out of control, and the ability to proliferate indefinitely is mainly due to the loss of growthContact suppression；At the same time, it can secrete growth factors that stimulate its own proliferation to promote its own division;Lost the mechanism of programmed decline;LostGap connection, which makes the cells lose communication and coordination in metabolism and division and differentiation.
cell canceration
2. It is easy to disperse and metastasize because cancer cells can synthesize and secrete someprotease, degradationcell surfaceSome structures ofExtracellular matrixinFibronectinThe intercellular viscosity decreased significantly;At the same time, due toGolgi apparatusSome are missing fromGlycosyltransferase, makeMembrane proteinSynthesis is blocked.Cancer cells can pass in and out of capillaries and metastasize in the body over a long distance through the circulatory system.
3. CellsMorphogenesisThe morphological characteristics of all cancer cells in the significantly changed individuals are similar, but they are similar to the surroundingnormal cells They often differ greatly.This is due to theCytoskeletonThe composition is reduced, and the arrangement is disorderly.
Virus carcinogenesis may be caused by the integration of viral genetic material (DNA or RNA) intoHost cellThe DNA strand of the cell will mutate, and the proto oncogene or tumor suppressor gene will mutate, which will affect the synthesis of protein and the change of cell function and structure.
Prevention: try to avoid contact with physical, chemicalVirusesAnd so onCarcinogen。At the same time, we should pay attention to strengthening our physique, maintaining a healthy mentality, developing good living habits, and actively taking protective measures from various aspects.
Canceration gene
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oneProto oncogeneProto oncogenes exist in all normal cells and have the potential to cause cell canceration.
threeOncogeneOncogenes can be divided into two categories in terms of their origin: one is the mutation of proto oncogenes, calledCellular carcinomaGene (c-onc) is proto oncogeneAllele；The other isViral oncogene（v-onc）.
Canceration factor
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Long term external factor stimulation, such as smoking, drinking, eating hot food (esophageal cancer), and long-term consumptionPickleFood (digestive tract tumor)Aflatoxin（liver cancer）Colchicineetc.
In addition, depression and other factors will makeApoptosisSystematicImmune surveillanceAbnormal, leading to abnormal cell proliferation and failure to induce apoptosis in time, causing tumor.
Tumor is caused by abnormal proliferation of normal cells, not normal cells into cancer cells.
