Human red blood cells have no other membrane structure outside the cell membrane
Erythrocyte membrane is that human red blood cells have no other membrane structure outside the cell membrane. Because it is easy to get the empty shell of the cell membrane through hemolysis, it is often used as a model of living membrane for research.
- Chinese name
- Erythrocyte membrane
- Foreign name
- erythrocyte membrane，red cellmembrane
- Discipline
- biology
- Headword
- Erythrocyte membrane
Main components
Its main components are protein (about 49%, weight ratio) and lipid (about 44%), as well as sugar. Lipids are composed of phospholipids (about 73%, weight ratio), cholesterol (about 22%) and glycolipids (about 5%). Phospholipids consist of lecithin Phosphatidylethanolamine 、 Phosphatidylserine And sphingomyelin. These phospholipids are not evenly distributed in the membrane. Most of them contain neutral phospholipids with bile base on the surface layer, while the inner layer contains phosphoacylsserine with negative charge and phosphatidylethanolamine with variable structure. The protein composition is shown in the table. When the empty shell of the cell membrane is treated with hypotonic solution, the haemorrhagic shadow protein and Actin After being treated with hypertonic solution, anchor protein and 4.1 bands were released. These are called Peripheral protein （peripheral protein）。 With 3 useful surface active agent The membrane can be dissolved only after its structure is destroyed. Such proteins are called Intrinsic protein （integral protein）。 Blood group glycoprotein It is also intrinsic, and it is a MN blood type substance containing the sugar chain of sialic acid. Band 3 also contains sugar chain, which has anion channel function. Haemoglobin, actin and band 4.1 form a reticular structure. Anchorin binds to band 3 and Haemoglobin on the membrane to connect with the reticular structure. [1] 
