Sodium phosphate, chemical formula: NathreePOfour, is a phosphate.It is easy to be deliquescent and weathered in dry air to generate sodium dihydrogen phosphate and sodium bicarbonate.It is almost completely decomposed into disodium hydrogen phosphate and sodium hydroxide in water.It is used in electroplating industry to prepare degreasing solution for surface treatment and alkaline detergent for unpolished parts.In the synthetic detergent formula, due to its high alkalinity, it is only used in the strong alkaline detergent formula, such as car cleaner, floor cleaner, metal cleaner, etc.
Reference value for drainage parameter calculation (XlogP): None
Number of hydrogen bond donors: 0[3]
Number of hydrogen bond receptors: 4[3]
Number of rotatable chemical bonds: 0[3]
Number of tautomers: 0
Topological molecular polar surface area: 86.2[3]
Number of heavy atoms: 8[3]
Surface charge: 0[3]
Complexity: 36.8[3]
Number of isotope atoms: 0[3]
Determine the number of atomic structure centers: 0[3]
Number of uncertain atomic structure centers: 0[3]
Determine the number of chemical bond structure centers: 0[3]
Number of uncertain chemical bond structure centers: 0[3]
Number of covalent bond units: 4[2]
toxicology data
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Minimal lethal dose (rat, vein) 1580mg/kg.Groundhog oral LDfifty: More than 2g/kg.[2]
application area
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Medical field
Indications: polycythemia vera, primary thrombocytosis, chronic myeloid leukemia, chronic lymphocytic leukemia, etc., as well as the identification of the nature of superficial masses, and also for the application treatment of neurodermatitis, chronic eczema, capillary tumor, keloid scar, pterygium, corneal neovascularization, plasmacytoma, etc.
Usage and dosage: polycythemia: oral, 222MBq~296MBq (6mCi~8mCi) per course of treatment.Chronic leukemia: intravenous injection, 148MBq~185MBq (4mCi~5mCi) per course.The nature of diagnosis of superficial mass: oral, 7.4MBq ～ 11.1MBq (0.2mCi ～ 0.3mCi).After oral administration, the radioactivity of the tumor and the corresponding part of the healthy side were measured at 24h, 48h and 72h, respectively. If the ratio was>125%, the possibility of malignant disease was greater.Application treatment: The dose depends on the type and degree of the lesion, and usually adopts fractional irradiation.
Precautions: Take orally on an empty stomach.Low phosphorus diet is required for one week before and after taking 32P, and phosphorus containing drugs are prohibited.The interval between repeated treatment shall be at least two months, and the dosage shall be less than that of the first treatment.Do not use it for patients under 20 years old, pregnant women, lactating women, liver and kidney insufficiency, severe anemia, bleeding tendency, etc.
Food field
1. The product quality improver can improve the complexed metal ions, pH value and ionic strength of food, thus improving the cohesion and water holding capacity of food.China stipulates that it can be used for cheese, and the maximum dosage is 5g/kg;The maximum dosage in western ham, meat, fish, shrimp and crab is 3.0g/kg;The maximum use amount in cans, fruit juice, beverages and dairy products is 0.5g/kg.
2. It is used as analytical reagent, water softener and sugar purification.
Industrial field
It is used as water softener and detergent, boiler scale inhibitor, color fixing agent in printing and dyeing, mercerizing enhancer of fabric, metal corrosion inhibitor or rust inhibitor.Enamel industry is used as flux and decolorizing agent.Used as degreasing agent and degumming agent in leather industry.[1]
security information
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Safety terminology
S24/25：Avoid contact with skin and eyes。
Avoid skin and eye contact.
S26：In case of contact with eyes， rinse immediately with plenty of water and seek medical advice.
In case of contact with eyes, please immediately flush with plenty of water and seek medical advice.
S36/37/39：Wear suitable protective clothing， gloves and eye/face protection.
Wear appropriate protective clothing, gloves and goggles or mask.
S45：In case of accident or if you feel unwell， seek medical advice immediately （show the label whenever possible.）
In case of accident or discomfort, seek medical advice immediately (show the label if possible).
Risk terminology
R34：Causes burns.。
Causes burns.
R36/37/38：Irritating to eyes, respiratory system and skin.
