small peptide

Terminology in biochemistry and molecular biology
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Short peptide, Short chain Short chain polypeptide is short for peptide. The source of short peptide can be divided into two categories, one is peptide synthesized from 2~10 amino acids through protein, the other is peptide composed of protein degraded to 2~10 amino acids, also known as small peptide, oligopeptide. [1 ]
Chinese name
small peptide
Foreign name
Short chain polypeptide
Full name
Short chain peptide
Discipline
Biochemistry and Molecular Biology

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Peptides are substances between amino acids and proteins. The molecule of amino acid is the smallest, the protein is the largest, and there are two or more Amino acid dehydration condensation Form several Peptide bond Thus, a peptide is formed, and multiple peptides are folded to form a protein molecule. Peptides are precise protein fragments, whose molecules are only nanometers in size, which can be easily absorbed by gastrointestinal tract, blood vessels and skin. Short peptide, short chain peptide for short, is composed of amino acid composition Protein fragments of.

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Peptides are α - amino acids Peptide chain The compound formed by connecting together is also Proteolysis Of Intermediate product
Generally, the number of amino acids contained in peptides is from two to nine. According to the different names of the number of amino acids in peptides, two amino acid molecules dehydration synthesis The resulting compound is called Dipeptide Similarly Tripeptide , tetrapeptide, pentapeptide, etc., up to nine peptides. Usually, the compounds formed by dehydration and condensation of 10~100 amino acid molecules are called polypeptides. Their molecular weight is less than 10000 Da (Dalton, Dalton), and they can penetrate Semipermeable membrane , not by Trichloroacetic acid and ammonium sulphate Precipitated. There are also literatures that describe peptides composed of 2~10 amino acids as Oligopeptide Also called short peptide;
Peptides composed of 10~50 amino acids become polypeptides, and peptides composed of more than 50 amino acids are called proteins.

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In general, short peptides are digested in the gastrointestinal tract Absorption ratio Protein free amino acid The digestion and absorption are good and fast, and the retention time of short peptides in the stomach is shorter than that of proteins, Gastroptosis The frequency of feeling abdominal fullness is low, and the absorption area of small intestine is reduced.
Short chain polypeptides play a more active role in the life process than amino acids protein synthesis Catabolism Process. As a way of protein supplement, for healthy people, it is mainly to obtain various short peptides and l-amino acid It provides synthetic hormones, enzymes and proteins in the body.
Human body sub-health The direct use of short peptide products in the state of illness or illness plays an important role in restoring human vitality.

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In recent years scientific research It is found that the main form of protein absorbed by the human body is not amino acids, but short peptides. This is a major breakthrough in the study of the mechanism of protein absorption by the human body, with ten major characteristics:
1. Direct absorption without digestion. Generally, short peptides are synthesized by the human body itself, which is the enzymatic hydrolysis of the nutrients eaten by the human body. It has been synthesized in vitro and can be directly absorbed without secondary degradation after entering the human body.
2. It is absorbed quickly, and the oral dosage is like Injection Oral administration into the human body is as fast as a rocket. Some scientists call it "biological missile". It quickly passes through the mouth and stomach of the human body, directly enters the small intestine, is absorbed by the small intestine, and finally enters the human body The blood circulatory system Organs and cell tissues can rapidly exert their physiological and biological functions.
3. Absorb in complete form. The peptide itself has a protective film, which will not be affected by the human body's enzymes Pancreatin amylase digestive enzyme Pepsin and digestive system The short peptide is absorbed and utilized by the human body in a complete form due to the damage or secondary hydrolysis of acid-base substances in.
4. The short peptide is 100% absorbed by human body. After absorption, there will be no Excreta , fully absorbed and utilized by human body.
5. Short peptides are actively absorbed by human body. The short peptide has its own activity and energy Active absorption Forced absorption is the function of its own activity and energy. Therefore, when it is absorbed by the human body, it is not that the human body needs to consume its own energy to absorb it, but that polypeptides can be absorbed by the human body with their own energy.
6. The short peptide is preferentially absorbed by human body. What people usually eat Nutrients In terms of absorption, short peptides have the characteristics of preferential absorption in competition with short peptides, which is inseparable from the characteristics of active absorption.
7. Short peptides can protect amino acids when absorbed by human body. It can protect amino acids from damage. Therefore, the mixture of peptide and amino acid is the best absorption mechanism for human body to absorb protein.
8. Short peptides act as carriers in human body. Nutrients that people usually eat, especially calcium, are beneficial to human body trace element , adsorption, pasting and loading on the body.
9. Short peptide can rise in human body Means of transport Role of. It can adsorb various nutrients that people usually eat on the body, and then transport them to various cells, organs and tissues of the human body, which can be absorbed and used by the human body together, playing their different functions.
10. After being absorbed by the human body, the short peptide plays a messenger role in the human body. It acts as Neurotransmitter Transmit information so that all systems, organs and tissues of the human body can play their own and Overall effect