Pruritus

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synonym skin Itch (Itchy skin) generally refers to pruritus
Yang Xueyuan (Chief Physician) Review Dermatology Hospital of Chinese Academy of Medical Sciences
Li Chengrang (Deputy Chief Physician) Review Dermatology Hospital of Chinese Academy of Medical Sciences
itch It is a kind of skin itching without Primary Skin damage Of skin disease symptom. According to the scope and location of skin itching, it is generally divided into two categories: systemic and localized.
TCM disease name
Pruritus
Foreign name
pruritus
Visiting department
the skin department
Common causes
Environmental factors, external drugs, certain stimuli, primary diseases, etc
common symptom
Paroxysmal itching, severe at night, with scratches, blood scabs, pigments, etc

pathogeny

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1. Systemic pruritus is often the companion or first symptom of many systemic diseases, such as uremia Biliary cirrhosis Hyperthyroidism Or decrease diabetes Malignant tumor And nerves psychogenic pruritus Etc. Generalized pruritus external cause And environmental factor (including humidity, season, biology or chemistry in the working environment material Irritation), topical drugs, alkaline soap and sebaceous glands And Sweat gland Decreased secretory function xerosis cutis And so on.
2. The cause of localized pruritus is sometimes the same as that of systemic pruritus, such as diabetes Anal pruritus Many and Enterobiasis , hemorrhoid Anal fistula And so on. vulva Pruritus is often associated with leucorrhea and vagina Trichomoniasis , vaginal mycosis gonorrhea and cervical carcinoma of Scrotal pruritus is often associated with high local skin temperature hyperhidrosis , friction mycotic infection of The occurrence of itching is mainly caused by chemical agents such as histamine Substance P Kinin and protease Caused by the release of.

clinical manifestation

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1. Systemic pruritus
It is commonly seen in adults, and itching often starts at one place and gradually extends to the whole body. It is often paroxysmal, especially at night. In severe cases, it is persistent itching with paroxysmal exacerbation. Drinking, coffee, tea, emotional changes, spicy food stimulation, mechanical scratching, warm bedding, and even some hints can all promote the onset and aggravation of itching. Frequent secondary scratches encrusted blood , pigmentation, even eczema Anamorphosis Lichenoid transformation Pyoderma as well as Lymphangitis and lymphadenitis
(1) Senile pruritus It usually occurs in the elderly, and the trunk is often the most itchy. It is mostly caused by factors such as sebaceous gland dysfunction and dry skin. Female patients may be a manifestation of postmenopausal syndrome.
(2) Pruritus in winter It is mostly seen in adults, and children can also get sick. It usually occurs in the late autumn and winter when the temperature changes sharply. The patient often starts itching when entering a warm room or undressing before going to bed.
(3) Pruritus in summer Often Damp heat Itch caused by inducement, summer sweat The increase may aggravate itching.
2. Localized pruritus
(1) Anal pruritus Mostly seen in middle-aged men, with Enterobiasis Children can also get sick. Itching is generally confined to the anus and its surrounding skin, and can sometimes spread to the perineum, vulva and scrotum. Due to frequent scratching, only the anal skin is hypertrophic, which can also be lichen like or eczema Anamorphosis, etc secondary Damage.
(2) Pruritus scrotum Itching is mainly confined to the scrotum, sometimes involving the penis, perineum and anus. Due to constant scratching, it causes lichen like changes eczema Anamorphosis and Secondary infection Etc.
(3) Pruritus vulvae Itching often occurs on the large and small labia. Due to constant scratching, the labia often has hypertrophic skin and maceration, clitoris And vaginal mucosa may have redness, swelling and erosion.

diagnosis

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According to the fact that there was only itching at the beginning, but no Primary skin lesions It can be confirmed. In order to find the cause of the disease, we should inquire about the medical history in detail, and do a comprehensive physical examination and necessary laboratory examination

differential diagnosis

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This disease needs eczema , insect bite dermatitis, lice Scabies , atopic dermatitis Neurodermatitis And nodular prurigo.

treatment

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The key to prevention and treatment is to find the cause and avoid the inducing factors. Avoid scratching, rubbing, hot water scalding and other methods to relieve itching. Life should be regular, clothes should be soft, don't bathe too often. Avoid drinking Strong tea And edible Pepper , pepper and mustard Such spicy and stimulating food. Patients with mental tension and restlessness should pay attention to rest and properly change the bad environment
1. External treatment
(1) Low pH Cleaning agent And lubricants.
(2) Coolant and local anesthetics include menthol camphor Carbolic acid , Bureau anesthetic lidocaine and Prilocaine Mixture of Enna (EMLA)。
(3) External use Antihistamine And external use Glucocorticoid
(4) Immunosuppressant
(5) Strontium salts.
2. Systematic treatment
(1) Antihistamine Calcic agent vitamin C Sodium thiosulfate And sedative hypnotic drugs can be used according to the patient's condition.
(2) Systemic pruritus available Procaine hydrochloride Venous occlusion.
(3) Thalidomide (Thalidomide) to treat inflammation skin disease
(4) Opioid receptor Antagonist naloxone treatment bile Sexual pruritus and uremia Sexual itching is effective.
three physicotherapeutics Phototherapy
Inflammatory skin disease and uremia Primary Cholestasis and Polycythemia vera Itching caused by systemic diseases is effective.