Skin reaction is a kind of skin pathological reaction caused by external factors such as air and climate, including itching, redness, induration and blister.
- Chinese name
- Skin reaction
- Foreign name
- The skin reaction
- Substantive
- Severe skin reaction
- Reaction
- Pain, itching, redness, induration and blisters
case
Taken by Asian patients carbamazepine May cause severe skin reaction After the US Food and Drug Administration issued a safety message warning that Asian patients should undergo blood genetic examination before using carbamazepine, Health Canada Recently, carbamazepine (trade name: Delito ）The latest security information for. The notice said that there was a risk of serious skin reactions in Asian patients taking carbamazepine, including Stevens Johnson syndrome (SJS) and toxic epidermal necrolysis (TEN). Carbamazepine is mainly used to treat epilepsy Mania , bipolar disorder and Trigeminal neuralgia 。 The Ministry of Health of Canada announced that serious skin reactions SJS and TEN caused by taking carbamazepine are very rare. Among all patients with these side effects, the probability of Asian countries is about 10 times higher than that of Western countries. Studies have shown that Asian patients are at greater risk of taking carbamazepine. Health Canada has revised the prescription information of Delidor, and is currently revising the prescription information of all carbamazepine like drugs. The newly added information includes: compared with non Asian patients, Asian patients have a greater risk of serious skin reactions; Gene detection is helpful to identify the special gene marker of Asian patients, which is related to the severe skin reaction caused by carbamazepine; Asian patients, especially Chinese patients, should discuss gene testing with their doctors to determine whether it will increase the risk of serious skin reactions.
Health Canada Remind the patient to pay attention to the following information: all patients taking carbamazepine In case of skin rash, redness of skin, blistering or peeling of eyes or mouth and high fever; Patients who have taken carbamazepine and have severe skin reactions, regardless of race, should not take carbamazepine again, but should Quick consultation Medical staff, choose alternative treatment; Do not stop taking carbamazepine before consulting a doctor. 
