Methyl isocyanate is an organic compound with chemical formula CfourteenHtwenty-twoNOfourPS，It is a light yellow oily liquid, easily soluble in organic solvents such as benzene, toluene, xylene, ether, and difficult to dissolve in water. It is mainly used as a new type of soil insecticide, with strong contact and stomach toxicity, wide insecticidal spectrum, long residual effect period, similar to phoxim, and is mainly used for wheat, peanut, soybean, corn, sweet potato, sugar beet, apple and other crops,It can be used to prevent and control underground pests such as grubs, mole crickets and golden needle worms, as well as slime worms, aphids, tobacco budworms, peach fruit borers, red spiders, etc.
In March 2022, in order to ensure the quality and safety of agricultural products, human and animal safety, and ecological environment safety, according to the Opinions of the CPC Central Committee and the State Council on Deepening Reform and Strengthening Food Safety, and the Regulations on Pesticide Management, and with the consent of the State Council, it was decided to take elimination measures for four highly toxic agricultural drugs, such as methyl isocyanate.Sales and use will be prohibited from September 1, 2024.As of September 1, 2022, the pesticide registration of its technical drugs and preparations will be revoked and production will be prohibited.The legally produced products can be sold and used within the warranty period, and are prohibited from sale and use since September 1, 2024[3]。[1]
Solubility: Easily soluble in benzene, toluene, xylene, ether and other organic solvents, but hardly soluble in water[2]
Molecular structure data
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Molar refractive index: 87.25
Molar volume (cmthree/mol）：281.8
Isotonic specific volume (90.2K): 723.6
Surface tension (dyne/cm): 43.4
Polarization (10-24cmthree）：34.59[2]
Calculate chemical data
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Reference value for drainage parameter calculation (XlogP): None
Number of hydrogen bond donors: 1
Number of hydrogen bond receptors: 6
Number of rotatable chemical bonds: 8
Number of tautomers: 2
Topological molecular polar surface area: 88.9
Number of heavy atoms: 21
Surface charge: 0
Complexity: 389
Number of isotope atoms: 0
Determine the number of atomic structure centers: 0
Number of uncertain atomic structure centers: 1
Determine the number of chemical bond structure centers: 0
Number of uncertain chemical bond structure centers: 0
Number of covalent bond units: 1[2]
toxicology data
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Acute toxicity: oral LD in male ratsfifty：21.52mg/kg；Oral LD of female ratsfifty：19.18mg/kg；Oral LD of male micefifty：24.99mg/kg；Oral LD in female micefifty：33.83mg/kg；Transdermal LD in male ratsfifty：76.72mg/kg；Percutaneous LD in female ratsfifty：71.13mg/kg。[2]
purpose
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It is mainly used as a new type of soil insecticide with strong contact and stomach toxicity. It has a wide range of insecticides and a long residual effect period. Its control effect on underground pests is similar to phoxim. It is mainly used for wheat, peanuts, soybeans, corn, sweet potatoes, sugar beets, apples and other crops. It can also be used to control underground pests such as grubs, mole crickets, and golden needle worms. It can also be used to control slime worms, aphids, tobacco budwormsPeach borer, spider, etc.
usage method
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1. Prevention and control of underground pests: 500 mL 40% emulsifiable oil can be used to control mole crickets, grubs and golden needle worms, 50-60 kg water can be added, and 500-600 kg wheat, corn or sorghum seeds can be mixed. The effective control period is generally about 30 days.To prevent and control peanut and soybean grubs, 20% emulsifiable oil 300-450mL per mu was used to make 20kg toxic soil at the sowing time. After hole and strip application, the soil was covered evenly, and the effect of seedling protection was good.To prevent and control white grubs in melon fields, 200mL of 20% emulsifiable concentrate or 100mL of 40% emulsifiable concentrate per mu and 5kg of bran shall be used as poison bait, which shall be applied in the ditch when planting watermelon.
2. Prevention and control of pests on the ground: 400mL of 20% emulsifiable concentrate and 100L of water shall be applied to the base of sugarcane seedlings per mu of sugarcane weevil and covered with soil.The peach fruit borer is sprayed on the soil surface in the tree tray with 500 mL of 40% emulsifiable concentrate and 150 L of water per mu.It is better to spray cotton weevil in the morning, with 25 mL of 40% emulsifiable concentrate per mu, and spray water.Aphid and armyworm are sprayed with 2000 times of 20% emulsifiable concentrates every time.
matters needing attention
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1. Methyl isocyanate is only allowed to be used for seed dressing or soil treatment, not for controlling vegetable pests and spraying fruit trees.
2. It is strictly prohibited to put livestock in the drug application area to avoid poisoning.
3. Methylisothion can cause poisoning through the esophagus, respiratory tract and skin, and the poisoned can be treated with atropine or triphosphadine.
4. Methyl isocyanate is prohibited to be used on vegetables, fruit trees, tea and Chinese herbal medicines.
security information
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Safety terminology
S36/37：Wear suitable protective clothing and gloves.
Wear appropriate protective clothing and gloves.
S45：In case of accident or if you feel unwell, seek medical advice immediately (show the lable where possible).
In case of an accident or feeling unwell, seek medical advice immediately (show the label if possible).
S60：This material and/or its container must be disposed of as hazardous waste.
The substance and its container must be disposed of as hazardous waste.
S61：Avoid release to the environment. Refer to special instructions/Safety data sheets.
Avoid releasing into the environment, refer to special instructions/safety receipt instructions.
Risk terminology
R24/25：Toxic in contact with skin and if swallowed.
Toxic in contact with skin and if swallowed.
R50/53：Very toxic to aquatic organisms, may cause long-term adverse effects in the aquatic environment.
It is extremely toxic to aquatic organisms and may cause long-term adverse effects in the aquatic environment.
