Studied in the preparatory course of Algol University.From 1953 to 1958, he served as an assistant researcher in the biophysical laboratory of the University of Geneva. In the late 59s and early 1960s, he and his colleagues further studied the heritable mutations of bacteriophages in parasites on the basis of S. Luria's research.He found that there were some bacteria that could change the DNA structure of bacteriophageRestriction endonuclease。They discovered restriction endonuclease and used itmolecular geneticsResearch.He became a lecturer in 1962, and was soon employed as a distinguished professor of molecular genetics.1970-1971, he was a specially invited researcher in the Department of Molecular Biology, University of California, USA.After 1971, he became professor of microbiology at the University of Basel[1]。
