This entry is missing Overview , add relevant content to make the entry more complete, and it can also be upgraded quickly. Hurry up edit Come on! Conformational disease is a disease name.
- TCM disease name
- Conformational disease
- Common causes
- Abnormalities caused by changes in the spatial conformation of proteins
The three-dimensional spatial structure of protein is called protein conformation. The specific conformation is the structural basis for protein to perform its function. The abnormal disease caused by the change of protein spatial conformation is called conformation disease. Such as mad cow disease. Mad cow disease（ Bovine spongiform encephalopathy Bovine encephalopathy BSE) is a new type of Alzheimer's disease Symptom New Creutzfeldt Jakob disease , is a chronic, fatal, degenerative neurological disease. It is caused by prion, a pathogen whose essence has not yet been fully understood. Normal people and Animal cell There are prion proteins in it. Under the action of unknown reasons, its three-dimensional structure changes, α - helix content decreases, and β - folding increases, making normal proteins become infectious proteins, thus leading to the occurrence of diseases. 
