Maximum efficiency is intended toMaximum effectpower;It is generally called efficiency.systemPharmacodynamicsMedium, whichDose effect relationshipOne of the basic effect concepts of.medicineThe effect of is increased with the increase of dose (concentration) until it reaches the limit of effect, which is called the maximum effect force.
This has the same meaning as the maximum effect (see "maximum effect").When comparing the efficacy of similar drugs, the maximum efficacy of each drug is usually expressed by the absolute value of the efficacy index (rather than the relative value, i.e. 100%), which is called efficacy;At the same time, some people often refer to the relative value of the maximum effect force (i.e. 100%) as the maximum effect (Emax) for researchDose effect curveGeneral rules of.When clinicians choose drugsbe similarThe higher efficiency is usually selected, such asFurosemideIs more effective thanChlorothiazideClass.
Maximum response drugIntrinsic activity, in direct proportion, that is, the greater the maximum efficiency, the greater the intrinsic activity.
