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Compound amino acid injection

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Compound amino acid injection
Amino acid drugs. It is used for patients with insufficient protein intake, absorption disorders and other amino acids that cannot meet the metabolic needs of the body. It is also used to improve the nutritional status of patients after surgery.
Drug name
Compound amino acid injection (15AA)
Foreign name
Compound Amino Acid Injection(l5AA)
Prescription medicine or not
prescription
Main indications
Supplement amino acid and improve the nutritional status of patients after operation.
Adverse reactions
Rash like allergic reaction; Occasionally nausea, vomiting, chest tightness, etc
Main drug contraindications
Severe liver and kidney dysfunction, amino acid metabolism disorder, etc
Dosage form
injection
Careful use by athletes
Inadvertent use
Whether included in medical insurance
bring into
Drug type
chemical

Composition

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This product is a compound preparation. It is a sterile aqueous solution prepared from 15 kinds of amino acids. Its components are
L-proline (C5H9NO2) 8.0g
L-serine (C3H7NO3) 5.0g
L-alanine (C3H7NO2) 7.7g
L-arginine (C6H14N4O2) 6.0g
L-histidine (C6H9N3O2) 2.4g
L-tryptophan (C11H12N2O2) 0.66g
L-valine (C5H11NO2) 8.4g
L-threonine (C4H9NO3) 4.5g
L-leucine (C6H13NO2) 11.0g
L-methionine (C15H11NO2S) 1.0g
L-isoleucine (C6H13NO2) 9.0g
L-phenylalanine (C9H11NO2) 1.0g
L-lysine acetate (C6H14N2O2 · C2H4O2) 8.6g
L-cysteine hydrochloride (C3H7NO2S · HCl)<0.2g
Glycine (C2H5NO2) 9.0g
Sodium bisulfite (NaHSO3) 0.5g [1]

Preparation and specification

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Compound amino acid injection (15AA) (1) 500ml: 40g (total amino acid); (2) 250ml: 20g (total amino acid); (3) 100ml: 8g (total amino acid)

Usage and dosage

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Intravenous drip, 250~500ml a day. Mix appropriate amount of 5%~10% glucose injection and drip slowly. The dropping rate should not exceed 20 drops per minute. [2]

Adverse reactions

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This product can cause rash like allergic reaction, and should be stopped once it occurs. Occasionally, nausea, vomiting, chest tightness, palpitations, chills, fever or headache occur.

taboo

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It is forbidden for patients with severe liver and kidney dysfunction, severe uremia and patients with metabolic disorder of amino acids. Patients with severe acidosis and congestive heart failure should use it with caution.

matters needing attention

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1. The infusion speed should be strictly controlled. 2. This product is hydrochloride, and a large amount of input may lead to acid-base imbalance. When a large number of electrolytes are used or used together for infusion, attention should be paid to the electrolyte and acid-base balance. 3. The liquid medicine must be carefully checked before use. If the bottle body is found to be broken, leaking, discolored, moldy, precipitated, deteriorated and other abnormal phenomena, it should never be used. 4. Crystallization may occur when it is cold. You can heat the solution to 60 ℃, shake it slowly to make the crystallization completely dissolved before reuse. 5. The open bottle liquid medicine is used up at one time, and the remaining liquid medicine should not be stored and reused.

Drugs for pregnant and lactating women

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This product has not been used in pregnancy and lactation. If it needs to be used, the advantages, disadvantages and risks should be weighed. Animal experiments (embryotoxicity study on rabbits) show that this product has no direct or indirect harmful effects on reproduction.

Children's medication

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This product is not suitable for children under 2 years old, because the prescription of this product is not suitable for the needs of these patients. Children over 2 years old also have no experience in using it, so it is not recommended for children.

Medication for the elderly

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The experiment was not conducted and there was no reliable reference.

Pharmacology and toxicology

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This product can promote normal protein metabolism, correct negative nitrogen balance, supplement protein and accelerate wound healing. This product can also adjust the plasma amino acid profile of patients with liver disease, increase the ratio of straight chain amino acid to aromatic amino acid and nutrition, provide tolerable nitrogen sources for patients with liver disease, improve protein levels, and promote the recovery of liver function. [1]