To understand gene inactivation, we must first understand what is antisense technology. "Antisense technology refers to a kind of RNA molecule that exists naturally or is artificially synthesized. It cannot encode protein, but its nucleotide sequence can complement and pair with a certain mRNA, so this Antisense RNA It can be paired with mRNA to interfere with the translation of mRNA, so that the corresponding gene cannot be expressed. This technology that uses antisense RNA to block a gene (target gene) becomes antisense technology. "—— Introduction to Biotechnology (Author: Song Siyang, Lou Shilin, Xiamen University). If it is used for cancer treatment, antisense RNA can be designed for oncogenes and introduced into cells to inhibit the expression of oncogenes, that is, gene inactivation, so as to achieve the purpose of cancer treatment. This is also true in the treatment of other diseases.
