Appearance: white to off white crystalline powder[2]
Molecular structure data
Molar refractive index: 95.09
Molar volume (cmthree/mol）：284.3
Isotonic specific volume (90.2K): 706.0
Surface tension (dyne/cm): 37.9
Polarization (10-24cmthree）：37.69[2]
Calculate chemical data
Reference value for drainage parameter calculation (XlogP): None
Number of hydrogen bond donors: 0
Number of hydrogen bond receptors: 2
Number of rotatable chemical bonds: 3
Number of tautomers: 0
Topological molecular polar surface area: 37.6
Number of heavy atoms: 23
Surface charge: 0
Complexity: 417
Number of isotope atoms: 0
Determine the number of atomic structure centers: 0
Number of uncertain atomic structure centers: 0
Determine the number of chemical bond structure centers: 0
Number of uncertain chemical bond structure centers: 0
Number of covalent bond units: 1[2]
Brief Introduction to Drugs
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indication
Treatment of occasional, temporary, chronic insomnia.
pharmacology
Zolpidem is an imidazolium pyridine derivative, which has a strong sleep inducing effect and is fast. It takes effect 30 minutes after taking the medicine.Since its half-life in blood is about 2.5 hours, it is a short-term hypnotic.Sleep research found that zolpidem mainly acts on the second sleep phase of the non rapid eye movement phase of the sleep cycle, increases or does not increase slow wave sleep, and has a slight effect on the rapid eye movement phase.If the drug is stopped, compared with other drugs, the sleep disorder caused by it is relatively mild.
matters needing attention
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1. There are dizziness, lethargy, nausea, headache, memory loss, restlessness at night, diarrhea, falls and so on.
2. If you have kidney disease, liver disease, dyspnea and muscle disease (such as myasthenia), you must inform your doctor.
3. The elderly should take it carefully.
4. During the period of taking medicine, people should drink alcohol sparingly.
5. It may reduce the attention of drivers and machine operators.
6. After taking a sleeping pill, if you get up in the middle of the night, there may be: slow reaction, danger of falling, dizziness.
7. Children under the age of 15, pregnant women and women who are breast-feeding must consult a doctor or pharmacist.
