Tert butyl group, molecular formula: - C (CH3) 3, English name: tert butyl group.It is also called tertiary butyl or tert butyl.yes2-Methylpropane(NotNeopentane, YesIsobutane）, removed from the moleculeMethylene(Level IIIcarbon atom, ∨ CH).
Tert butyl structural formula
The steric hindrance of tert butyl is large.
Tert butylSystem nomenclatureThe name is 1,1-dimethylethyl, because of its large steric hindranceOrganic reactionThe obviousSpatial effect。Uncle RuButylbenzeneThe tert butyl in is basically an adjacent para positioning group, but due to the influence of tert butyl space effectSubstituentThis effect is more obvious when the new substituent also has strong steric hindrance.
Tert butyl effect
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The tert butyl substituent is aSteric hindranceLarge groups, often used together with other large steric groups for kinetic stability in chemical synthesis, such asTrimethylsilylGroup.Tert butyl forchemical reactionThe influence exerted by the process is called "tert butyl effect".This effect is deduced from the Diels Alder reaction as follows: tert butylSubstituentOfreaction rateCompared withhydrogen atomAs a substituent, it is 240 times higher.
