Monocytes are the largest in the bloodblood corpuscle, which is also the largestwhite blood cell, is an important part of the body defense system.Monocytes derived from bone marrowHematopoietic stem cells, and onbone marrowThey are still immature cells when they enter the blood from the bone marrow.Monocytes also participate in the immune response, and after phagocytosis of antigens, they will transfer the antigen determinant they carry tolymphocyteAnd induce specific immune response of lymphocytes.Monocytes are also the main cell defense system against intracellular pathogenic bacteria and parasites, and also have the ability to identify and kill tumor cells.Compared with other blood cells, monocytes contain more non-specific esterase and have stronger phagocytosis.When inflammation or other diseases occur in the body, the percentage of the total number of monocytes can change, so checking the monocyte count becomes an important method for auxiliary diagnosis.
Phagocytosis of foreign bodies to produce antibodies
Clinical significance
Announce
edit
The number of monocytes changes due to physiological and pathological factors, as follows:
1. Increase
(1) Physiological increase is more common in infants and children;
(2) Pathological increase: ① some infections, such as typhoid fever, tuberculosis, malaria, etc.; ②Some blood diseases, such as monocytic leukemia, lymphoma, Hodgkin's disease, etc.; ③Acute infectious disease or recovery period of acute infection.
2. Decrease
It has no clinical significance, because the content of monocytes in human body is very small.
