The exact location where the gene marker M96 first appeared in northeast Africa is still unclear 30000 to 40000 years ago. About 50000 years ago, a Middle East clan began to move out of Africa for the second wave of migration. Most of them are descendants of the gene marker M89. The Middle East clan moved northward and finally settled in the Middle East. [1]
Haploid group E also came to the Middle East, and the specific route may be the same as or different from that of the Middle East clan. [1]