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Secretory vesicles are vesicles formed in the regulatory pathway. The formation mechanism of these vesicles is different from that of the assembled secretory vesicles.In some specialSecretory cellSynthesis of some special products, such as hormones, mucus, digestive enzymes, which are first stored in secretory vesicles. These vesicles leave the reverse Golgi network through budding and gather inCell plasma membraneNearby, when cells are stimulated by extracellular signals, they will fuse with the cell plasma membrane to release the contents outside the cell.If blood sugar increases, cells will send signals to release insulin.
Chinese name
Secretory vesicle
Foreign name
secretory vesicles
Nature
Vesicles formed in regulatory pathways
Features
Storage such as hormone, mucus, digestive enzyme, etc
Regulatory secretion has two characteristics: first, the formation of vesicles is selective;The second feature is its concentration, which can increase the concentration of transported substances by 200 times.
Efflux pathway
Announce
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(persistent exocytosis pathway): All eukaryotic cells haveGolgi apparatusTGN distinguishes the process of vesicle transport to the plasma membrane, and its role is to renew membrane proteins and lipids, form plasma membrane peripheral proteinsExtracellular matrix, or as nutrients and signaling molecules.The constitutive efflux pathway completes the protein transport process through the default path.stayRough endoplasmic reticulumExcept for some proteins with special marks that reside in ER or Golgi apparatus or selectively enter lysosomes and regulatory secretory vesicles, the rest of the proteins synthesized incell surfaceThis way completes the transport process. ②Regulated discharge pathway(regulated exocytosis pathway): Secretions produced by secretory cells (such as hormones, mucus or digestive enzymes) are stored in the secretory vesicles. When cells are stimulated by extracellular signals, the secretory vesicles fuse with the plasma membrane and release the contents.Regulatory efflux pathways exist in specializedSecretory cell。The protein sorting signal exists in the protein itself, which is selectively packaged as transport vesicles by special receptors on Golgi TGN.
