Agglutinogen

antigen

Collection

zero Useful+1

zero

Agglutinogen attached to red blood cell The surface is an antigen. lectin It exists in plasma (or serum) and is an antibody against the same name agglutinin. The same name agglutinin and lectin meet (e.g., agglutinin A and Anti A Lectin)^[1] happen Erythrocyte agglutination 。

Chinese name: Agglutinogen
Nature: Is a kind of antigen
Attachment position: red blood cell surface

Existing part: plasma
Classification: A agglutinogen and B agglutinogen
Constituent substances: glycoprotein

catalog

one Introduction to agglutinogen
two Agglutinogen component

Introduction to agglutinogen

Announce

edit

chart (1 sheet)

Anthropogenic red blood cell It contains two kinds of agglutinogen, called A agglutinogen and B agglutinogen Human serum contains two kinds of agglutinin lectin , respectively called Anti A Lectins and anti B lectins. Everyone's serum does not contain Erythrocyte agglutination Agglutinin of primary confrontation.

Only agglutinogen A on red blood cells is Type A blood , there is anti B agglutinin in its serum; Only agglutinogen B on red blood cells is type B blood, and there is Anti A Of lectin ； Both A and B agglutinogens on red blood cells are AB type blood, and there is no anti A and anti B agglutinin in its serum; The patients without both A and B agglutinogen on red blood cells are type O, and their serum contains both anti A and anti B agglutinin. Agglutinogen A red blood cell It can be agglutinated by anti A agglutinin; Anti B agglutinin can make Erythropoiesis Agglutination.

If the blood type is incompatible during blood transfusion, the input red blood cells will agglutinate, causing vascular obstruction and massive hemolysis in the blood vessels, resulting in serious consequences. So before transfusion Blood group identification 。 Normally, only ABO blood group The same can be transfused to each other. In case of emergency due to lack of homologous blood source, type O red blood cells will not be agglutinated because they have no agglutinogen, and red blood cells can be transfused to people of any other blood type. The AB type person has no agglutinin in the serum and can accept any type of red blood cells.

Agglutinogen component

Announce

edit

ABO blood group system Agglutinogen is glycoprotein 。 The protein part determines the blood type antigenicity Matter is composed of 11 kinds amino Polypeptide composed of acid, wherein threonine The content is the most, and others serine 、 proline Etc. Polysaccharide Partially Mucopolysaccharide , including D-galactose 、L- Fucose 、 N-acetyl-D-glucosamine , N-acetyl-D-amino Galactose Etc. The polysaccharide part determines the blood type Specificity Of.

Novice on the road

Growth task Getting Started with Editing Edit Rule Edit by myself

I have questions

Content query Online Service Official post bar Feedback

Complaints and suggestions

Report bad information Failed to appeal through entries Complaint of infringement information Blocking query and unblocking

Jinggong Network Anbei No. 1100000200001