Coagulation function refers to the ability of blood to change from flowing state to non flowing gel state, which is actually the solubility in plasmaFibrinogenTransinsolublefibrinFunction of.
In a narrow sense, it means that the body hasCoagulation factorGenerated by successively activating in a certain orderthrombinFinally makeFibrinogenBecome fibrin and promoteBlood coagulationAbility.The coagulation function in a broad sense also includesplateletActivity.
It can know whether the patient has abnormal coagulation function before the operation, effectively prevent bleeding during and after the operation and other accidents, so as to obtain the best surgical effect.
APTTIt is the most reliable one for the deficiency of endogenous coagulation factorsScreening test。APTT extension is mainly seen inhemophilia、DIC、hepatopathy, massive input of stored blood, etc;APTT shortening is mainly seen in DIC, prethrombotic state and thrombotic diseases;APTT can be used asheparinMonitoring indicators of treatment.
TTProlongation occurs at low or noneFibrinogenHematemiaAnd abnormal fibrinogenemia, increased FDP in blood (DIC), heparin andHeparinoidPresence of substances (such as heparin treatmentSLE、Liver diseaseEtc.).
There was once an emergency patientlaboratory examination When the coagulation test results showed that PT and APTT were prolonged, it was suspected that the patient had DICClinical LaboratoryUnder the advice of, the patient underwent a series of DIC tests, and the result was positive, but the patient did not show obvious DIC symptoms.If the patient is operated directly without blood coagulation test, the consequences will be unimaginable.A lot of such problems can be found from the blood coagulation function examination, which has bought more time for clinical timely detection and treatment of diseases.Coagulation series test is an important laboratory test for patients' coagulation function. It should be paid enough attention because it can detect abnormal coagulation function of patients before surgery.
