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Metabolic intermediate

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Substance generated during the change from starting substance A to final product X
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In the process of substance metabolism, the substance produced from the change of starting substance A to the final product X is called metabolic intermediate.
Chinese name
Metabolic intermediate
Foreign name
metabolic intermediate
Metabolic intermediate
In the form of pattern diagram, it is:
(2)
A→B→C→D→……→X
B, C, D, etc. in the formula are intermediate products. Metabolic intermediates generally cannot reach the concentration (or quantity) that can be easily detected during metabolism, but when the metabolism speed of a certain stage [such as (2) in the model diagram] is particularly slow than other stages, it will lead to the accumulation of its previous metabolic intermediate (B at this time). If appropriate reaction conditions are given, Proper pretreatment or the use of specific poisons will also strongly impede the progress of a certain reaction stage. According to the same principle, after removing natural or artificial mutants, diseases and organs Nutritional deficiency Many examples of the existence of normal metabolic intermediates can often be found in the study of abnormal metabolism when taking drugs. If the change of metabolic intermediates is further directly tracked and confirmed, the "isotope" test can be used.