Nitrosoguanidine

Chemical reagent products

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Nitrosoguanidine, melting point 118 ℃, crystalline, soluble in water, flammable, toxic, carcinogenic and irritating.

Chinese name: Nitrosoguanidine
Foreign name: nitroso-guanidin
English abbreviations: NTG

CAS No: 674-81-7
molecular weight: ： 88.07
Molecular formula: CH4N4O

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Medical applications

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chemical formula

1. Because it has the effect of inducing canceration, it is widely used by the medical community to study the mechanism of cancer.

Application of Microbial Breeding

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2. It is recognized as a chemical super mutagen with remarkable effect for mutation breeding.

The main principle used for mutation breeding is that nitrosoguanidine is an alkylating agent, which is quite effective in mutation Chemical mutagen , such mutagens have one or more active alkyl groups, which are easy to replace DNA molecule The active hydrogen atom in the DNA molecule causes the base and phosphoric acid on the DNA molecule to be partially alkylated, which causes the base pairing error during DNA replication and mutation.

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