Inhalation of the lowest toxic dose (TCLo) of 100ppm (6h) from 6 to 20 days after pregnancy in rats caused malformation of the urogenital system.The central nervous system and musculoskeletal system of hamsters were deformed by 238 mg/kg intraperitoneal administration 8 days after pregnancy.
5. Others
The lowest oral toxic dose (TCLo) of rats: 1120 mg/kg (6-15 days of pregnancy), which affects the number of fetuses per litter and causes embryotoxicity.[1]
In air, whenHydroxyl radicalThe concentration is 5.00 × 10fivePcs/cmthreeThe half-life of degradation is 83 d (theoretical).[1]
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Used as a selective solvent for separating hydrocarbons and refining petroleum fractions;It is used as organic synthesis raw material, solvent and resin additive.A small amount is used as medical raw material, mainly to synthesize the antispasmodic drug 2,4,6-trihydroxyphenylacetoneSulfamethoxazoleAnd other drugs.Also used aschromatographic analysis Reference materials;Also used as pesticideherbicideIntermediate of.
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Hazard Overview
Health hazard: the product releases cyanide ion in the body, which inhibitsRespiratory enzyme, causing hypoxia.
Acute poisoning: mild symptoms include headache, dizziness, fatigue, chest tightness, dyspnea, palpitations, nausea, vomiting, etc.Severe poisoning: prodromal stage: upper respiratory tract irritation, rapid breathing, headache, dizziness, chest tightness;Dyspnea: rising blood pressure, pulse rate, palpitations, bright red skin, chest compression, dyspnea, cyanosis, coma, etc;Paralysis period: continuous coma, muscle relaxation, respiratory and cardiac arrest and death.Eye and skin contact may cause burns, and absorption may cause poisoning.
Flammability and explosion hazard: the product is flammable, highly toxic and irritant.[1]
First aid measures
Skin contact: Take off contaminated clothes immediately, wash thoroughly with flowing clean water or 5% sodium thiosulfate solution for at least 20 minutes, and seek medical advice.
Eye contact: immediately lift the eyelids, thoroughly flush with a large amount of flowing water or physiological saline for at least 15 minutes, and then seek medical advice.
Inhalation: quickly leave the site to a place with fresh air to keep the respiratory tract unobstructed. If breathing is difficult, give oxygen.When breathing and heartbeat stop, perform artificial respiration (not mouth to mouth) and external chest compression immediately, inhale isoamyl nitrite, and seek medical advice.
Ingestion: drink enough warm water to induce vomiting.Use 1:5000 potassium permanganate or 5% sodium thiosulfate solution for gastric lavage and seek medical advice.[1]
Fire extinguishing method: spray water to cool the container, and move the container from the fire site to an open place if possible.
Extinguishing agent: insoluble foam, dry powder, carbon dioxide, sand.Fire extinguishing with water is invalid.[1]
Leakage emergency treatment
Emergency treatment: quickly evacuate the personnel in the leakage pollution area to the safety area, isolate them, and strictly restrict access.Cut off the ignition source.It is recommended that emergency personnel wear self-contained positive pressure respirators and anti poison clothing.Do not touch the leakage directly.Cut off the leakage source as much as possible.Prevent from flowing into restricted spaces such as sewers and flood discharge ditches.
Small amount of leakage: absorb or absorb with sand or other incombustible materials.A large amount of water can also be used for flushing, and the diluted washing water will be discharged into the waste water system.
Large amount of leakage: build a dike or dig a pit to receive.Cover with foam to reduce steam disaster.Use explosion-proof pump to transfer to tank car or special collector for recycling or transport to waste disposal site.[1]
Handling and storage
Precautions for operation: it shall be strictly sealed, and sufficient local exhaust and general ventilation shall be provided.The operation shall be mechanized and automated as far as possible.Operators must be specially trained and strictly abide by the operating procedures.It is recommended that operators wear self-priming filter type gas mask (full mask), one-piece adhesive tape gas suit and rubber oil resistant gloves.Keep away from kindling and heat sources, and smoking is strictly prohibited in the workplace.Use explosion-proof ventilation systems and equipment.Prevent vapor leakage into the air of the workplace.Avoid contact with oxidants, reducing agents, acids and alkalis.Load and unload gently during transportation to prevent damage to packaging and containers.Fire fighting equipment and leakage emergency treatment equipment of corresponding types and quantities shall be provided.Empty containers may leave harmful substances.
Precautions for storage: store in a cool and ventilated warehouse.Keep away from kindling and heat sources.The warehouse temperature should not exceed 30 ℃.Keep container sealed.It shall be stored separately from oxidants, reducing agents, acids, alkalis and edible chemicals, and shall not be mixed.Explosion proof lighting and ventilation facilities shall be adopted.It is prohibited to use mechanical equipment and tools that are easy to generate sparks.The storage area shall be equipped with leakage emergency treatment equipment and appropriate materials.The "five pairs" management system for extremely toxic substances shall be strictly implemented.[1]
