A841720

Based on20 reference（s）in Google Scholar 80 100 20

Axon2155

CAS[869802-58-4]

MFC17H21N5OS
W343.45

Purity：99%
单精度DMSO

A841720

说明，说明

Potent and selective non-competive mGlu1 receptor antagonist（IC50:10nM）；showing34-fold selectivity over mGluR5and no significant activity at other mGluR receptors，neurotransmitter receptors，ion channels，and transporters.A841720demonstrated full efficacy in various in vivo animal pain models。

KEYWORDS:A841720｜supplier｜mGluR1antagonist｜A841720｜CAS[869802-58-4]

GZ Zheng et al.Structure-Ativity Relationship of Triazafluorenone Derivatives as Potent and Selective mGluR1 Antagonists.J.Med.Chem.2005,487374-7388

O El-Kouhen et al.Blockade of mGluR1receptor results in analgesia and disruption of motor and cognitive performances:effects of A-841720，anovel non-competitive mGluR1receptor antagonist.Br.J.Pharmacol.2006149761-774

Non-competive mGluR1antagonist

Chemical name

9-（Dimethylamino）-3-（hexahydro-1H-azepin-1-yl）-pyrido[3'，2':4,5]thieno[3,2-d]pyrimidin-4（3H）-one

Parent CAS No。

[869802-58-4]

顺序，顺序

大小，大小	单位价格	Stock
5mg	€85.00	In Stock
25 mg	€335.00	In Stock

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