Nanning Cloud - Nanning News Network News (reporter Huang Xining, correspondent Li Fen) For Mr. Wu, a 43 year old citizen of Nanning, one of the most regrettable things in his life is that he stopped using anti hepatitis B drugs for nearly 10 years without listening to the doctor's advice.
Seven months ago, Mr. Wu went to Nanning Fourth People's Hospital for treatment due to abdominal pain. The doctor diagnosed that the primary liver cancer was in advanced stage.Active treatment such as transcatheter arterial chemoembolization and target drug free treatment has made him suffer from frequent fatigue, abdominal pain, anorexia, nausea and vomiting... Up to now, he has walked through a difficult seven month treatment journey, and young people have suffered mental and physical torture.
How far is the road from hepatitis B to liver cancer?This is a question in the mind of more than 70 million chronic hepatitis B patients in China.
A set of data shows that in 2022, there will be 367700 new cases of liver cancer in China, ranking fourth in malignant tumors.Liver cancer ranked second in the number of cancer deaths in China, with 316300.It is estimated that by 2040, the incidence and death of liver cancer in the world will increase by more than 55% compared with 2020, of which nearly half will occur in China.Hepatitis B virus is one of the important killers of liver cancer.In the study of liver cancer patients, 95% have evidence of hepatitis B virus infection, and about 10% have evidence of hepatitis C virus infection. Some patients are infected with two kinds of hepatitis viruses at the same time (but hepatitis A and hepatitis E rarely have the tendency of cirrhosis and liver cancer).That is to say, most patients with liver cancer are infected with hepatitis B virus, suffer from chronic hepatitis B, further develop to cirrhosis, and finally suffer from liver cancer, forming a three-step process of "hepatitis cirrhosis liver cancer".
The trilogy sounds terrible, but not all hepatitis B will inevitably evolve into liver cancer.According to statistics, 10%~30% of chronic hepatitis B patients develop into cirrhosis after at least 5-10 years, and 5-10% of cirrhosis patients turn into liver cancer after at least 5-10 years. Some patients also have cirrhosis and liver cancer simultaneously.
Chronic hepatitis B is a long-term battlefield between the liver and the hepatitis B virus. The liver tissue is repeatedly inflamed and necrotic. The liver is constantly fibrotic in the process of self repair, and finally gradually forms cirrhosis. Some patients further deteriorate into liver cancer.
The occurrence of liver cancer is indeed related to hepatitis B, but there is no need to panic. In fact, only a small number of people finally suffer from liver cancer, and liver cancer is not the inevitable destination of hepatitis B carriers.There is also an effective way to cut off the malignant transformation of "hepatitis B cirrhosis liver cancer".The first is to control the development of hepatitis and inhibit the massive replication of hepatitis B virus, so anti hepatitis B virus treatment is undoubtedly the most critical treatment method.The current anti hepatitis B virus drugs can only inhibit the replication of the virus, but have not yet been able to completely eliminate the hepatitis B virus from the human body. However, long-term use of anti hepatitis drugs to suppress the virus can reduce the inflammation of liver tissue, prevent and reduce liver fibrosis, inhibit these cancer promoting factors, and also play a role in preventing liver cancer.Some superior patients can achieve clinical cure and stay away from liver cancer.For people with hepatitis B, the purpose of regular physical examination is to find out whether there is high replication or low replication of hepatitis B virus in their own bodies, whether there is liver function damage and cirrhosis, and also to find early small primary liver cancer, and also to determine whether antiviral treatment is needed.
For those who have a history of hepatitis or HBsAg positive, natural population in high incidence areas of liver cancer, family history of liver cancer and other high-risk groups of liver cancer, physical examination should be carried out every 6 months, including liver function, HBV DNA, alpha fetoprotein, liver ultrasound and other examinations. If active hepatitis, cirrhosis changes, and liver cancer are found, active treatment should be carried out.The combination of regular serum alpha fetoprotein detection and liver ultrasound is an economical, practical and effective screening method for early liver cancer.
The liver is the only organ without pain nerve. It is a "mute" who does not cry or cry when sick.Liver cancer has become one of the most difficult cancers to be found at an early stage.The liver has no sense of pain, and patients with liver disease, especially those with hepatitis B or cirrhosis, should be careful when the following situations occur!We must not carry it hard, but should immediately carry out a detailed examination in the hospital to see if there is cancer, early detection and early treatment.
1. Unexplained fatigue;
2. Obvious emaciation in the short term;
3. Nausea, diarrhea, anorexia, abdominal distension, etc. are common digestive tract symptoms of liver cancer;
4. The phenomenon of low heat continues to occur at 37.5-38.5 ℃;
5. In patients with early liver cancer, bleeding tendencies such as gingival bleeding and subcutaneous ecchymosis often occur;
6. Liver pain.
Tips for daily liver protection:
1. Pay attention to food hygiene: Do not eat expired moldy food, and try to eat less pickled, smoked and roasted food. These foods contain aflatoxin, nitrosamines and other harmful factors that will damage the liver.
2. Do not drink or drink less: avoid alcoholic hepatitis and damage the detoxification function of the liver.Alcohol is the biggest risk factor for hepatitis B patients to transform into cirrhosis and liver cancer.It is reported that the canceration rate of hepatitis B patients who drink alcohol is three times higher than those who do not drink alcohol, and the harm of alcohol to hepatitis B patients cannot be underestimated.
3. Reasonable work and rest without staying up late: long-term fatigue, especially staying up late, is not conducive to the rest and self repair of the liver.
4. Strengthen physical exercise to prevent excessive sugar and fat intake: avoid fatty liver, diabetes and other liver cancer risk factors.
5. Eating more fruits and vegetables can effectively prevent liver cancer.
6. Keep a happy mood: anger hurts the liver, and bad emotions can also cause great damage to the liver.
