COPD may be caused by the following factors: First, long-term smoking, or even long-term inhalation of second-hand smoke, may lead to an increase in the incidence of COPD. In clinical practice, the middle-aged and elderly people who smoke for a long time have cough, chest tightness and other symptoms, so they need to go to the hospital to check COPD. 2、 Air pollution, for example, some women have no smoking history, but kitchen fume pollution may cause COPD. 3、 Genetic factors, such as α 1 antitrypsin deficiency, may cause complications such as emphysema and chronic obstructive pulmonary disease. 4、 Other reasons, such as low birth weight, may cause COPD. For another example, patients with asthma may also have COPD if they do not receive standard treatment and the disease continues to progress.