There are many reasons for being flustered and short of breath at night, which can be functional or organic diseases. Functional reasons can be found in physiological conditions, such as excessive tension and anxiety, excessive daytime fatigue, etc. It can also be seen in functional diseases, such as cardiac neurosis, mainly due to abnormal regulation of autonomic nerves. Organic diseases are most common in heart and lung diseases. Heart diseases can be seen in coronary heart disease, hypertensive heart disease, arrhythmia, and heart failure. Pulmonary diseases can be seen in bronchial asthma, chronic obstructive emphysema, pulmonary interstitial fibrosis, and lung tumors. It is necessary to actively identify the causes and deal with them accordingly.