Male scrotal pruritus is mostly caused by skin lesions at the scrotum, including infectious diseases of the scrotum. Severe scrotal infection can lead to acute cellulitis of the scrotum, which is an acute and diffuse suppurative infection. It starts quickly and can even cause scrotal gangrene. Other non infectious diseases, including scrotal tinea, lichen planus, sclerotic atrophic lichen, psoriasis, eczema, drug eruption and other diseases, can usually be characterized by itching, accompanied by papules, herpes, erosion, exudation, hypertrophy, infiltration, lichen like lesions and so on. In these cases, most patients can have severe itching. According to different types of lesions, different antifungal drugs, corticosteroids, and antihistamines are needed externally. Patients should pay attention to local cleaning, and if necessary, they should go to the corresponding dermatology department and urology department for treatment.