Onychomycosis is mainly caused by dermatophyte infection, most of which is directly infected by tinea manus and pedis. Genetic factors, systemic diseases such as diabetes, local blood or lymph flow disorders, nail trauma or other nail diseases may increase the probability of infection. The course of the disease is slow and can be prolonged for life if not treated. Patients generally have no conscious symptoms. Thickening or destruction of nails can affect the fine movements of fingers. It can also cause pain and secondary paronychia. Because drugs are not easy to enter under nails and nails grow slowly, it is difficult to treat. The key to treatment is to insist on medication. You can use a knife or nail file to remove the diseased nail as much as possible, then use 30% glacial acetic acid solution externally, and take itraconazole orally to improve the efficacy.