The headache of hypertensive patients after taking antihypertensive drugs is generally caused by the side effects of antihypertensive drugs. Of course, not all antihypertensive drugs will cause headache after taking them. The most common antihypertensive drugs with this symptom are calcium antagonists, such as nifedipine sustained-release tablets or controlled release tablets. In particular, this symptom is more obvious in the short acting nifedipine tablets, and headache may also occur in other drugs with vasodilator effects, such as isosorbide nitrate tablets. If you have headaches after taking antihypertensive drugs, you can continue to take them as long as you can tolerate them. After a period of adaptation, this symptom will disappear. If it is intolerable, it can be replaced with other antihypertensive drugs.